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    PESTICIDE RESIDUES IN FOOD - 1980


    Sponsored jointly by FAO and WHO






    EVALUATIONS 1980





    Joint meeting of the
    FAO Panel of Experts on Pesticide Residues
    in Food and the Environment
    and the
    WHO Expert Group on Pesticide Residues
    Rome, 6-15 October 1980



    The designations employed and the presentation of material in this
    publication do not imply the expression of any opinion whatsoever on
    the part of the Food and Agriculture Organization of the United
    Nations concerning the legal status of any country, territory, city or
    area or of its authorities, or concerning the delimitation of its
    frontiers or boundaries.

    M-84

    ISBN 92-5-101148-6

    All rights reserved. No part of this publication may be reproduced,
    stored in a retrieval system, or transmitted in any form or by any
    means, electronic, mechanical, photocopying or otherwise, without the
    prior permission of the copyright owner.  Applications for such
    permission, with a statement of the purpose and extent of the
    reproduction, should be addressed to the Director, Publications
    Division, Food and Agriculture Organization of the United Nations, Via
    delle Terme di Caracalla, 00100 Rome, Italy.

    (c) FAO 1981

    This document contains summaries of the data considered by the Joint
    Meeting of the FAO Panel of Experts on Pesticide Residues in Food and
    the Environment and the WHO Expert Group on Pesticide Residues, which
    met in Rome, 6 to 15 October 1980, together with the recommendations
    made.  A report of the 1980 Joint Meeting, which outlines the
    principles on which the evaluations were carried out and summarises
    the recommendations made, has also been published.*



              

    * Pesticide Residues in Food: Report of the 1980 Joint Meeting of the
    FAO Panel of Experts on Pesticide Residues in Food and the Environment
    and the WHO Expert Group on Pesticide Residues, FAO Plant Production
    and Protection Series No. 26, 1981.

    Previous FAO and WHO documentation is listed in Annex II.

    CONTENTS

    List of Attendees

    Introduction

    The Monographs

    Amitraz
    sec-Butylamine*
    Captan*
    Carbofuran*
    Carbophenothion*
    Chlordimeform
    Chlorobenzilate*
    Coumaphos*
    Cyanofenphos*
    Cyhexatin*
    2,4 - D*
    DDT*
    Deltamethrin
    Dithiocarbamates*
    Ethiofencarb*
    Etrimfos
    Fenamiphos*
    Fenthion*
    Guazatine*
    Imazalil*
    Iprodione*
    Maleic Hydrazide*
    Mecarbam
    Methacrifos
    Omethoate*
    Oxamyl
    Parathion-Methyl*
    Permethrin*
    Phenothrin
    Phenthoate
    Propargite*
       Compounds marked * have been evaluated previously.
    Annex I

    Annex II
    

    1980 JOINT MEETING OF THE FAO PANEL OF EXPERTS ON PESTICIDE RESIDUES
    IN FOOD AND THE ENVIRONMENT AND THE WHO EXPERT GROUP ON PESTICIDE
    RESIDUES

    Rome, 6 - 15 October 1980

    FAO Panel of Experts on Pesticide Residues in Food and The Environment

    Dr. D.C. Abbott, Deputy Director (Customer Services), Laboratory of
    the Government Chemist, Cornwall House, Stamford Street, London SE1
    9NQ, U.K.

    Dr. A. Ambrus, Department Head, Analytical Department, Plant
    Protection and Agrochemistry Centre, H-1502 Budapest, P.O.B. 127,
    Hungary.

    Prof. Dr. A.F.H. Besemer, Head, Pesticides Division, Plant Protection
    Service, Geertjesweg 15, 6706 EA Wageningen, Netherlands.

    Prof. Dr. G. Bressau, Chief, Pesticides Residues Unit, Pesticides
    Department, Federal Health Office, Bundesgesundheitsamt, Postfach
    330013, D-1000 Berlin 33.

    Dr. K.R. Hill, Chief, Analytical Chemistry Laboratory, U.S. Department
    of Agriculture, SEA/AR, Agricultural Environmental Quality Institute
    -ACL, Beltsville, Maryland 20705, U.S.A.

    Mr. N.F. Ives, Chemist, U.S. Environmental Protection Agency, Office
    of Pesticide Programs, Hazard Evaluation Division TS-769, CM No. 2,
    1921 Jefferson Davis Highway, Arlington, Virginia 22202, U.S.A.

    Dr. E.M. Thain, Deputy Director, Tropical Products Institute, 56/62
    Grays Inn Road, London WC1X 8LU, U.K.


    Observers Invited by FAO

    Mr. C.W. Collier, Pest Management Specialist, U.S. Agency for
    International Development DS/AGR, RPC 413C, Washington, D.C. 20530,
    U.S.A.

    Ir. A.J. Pieters, Directorate of Public Health, Foodstuffs Division,
    Dokter Reijersstraat 12, Leidschendam, Netherlands (Chairman of Codex
    Committee on Pesticide Residues).

    WHO Expert Group on Pesticide Residues

    Prof. C. Amerasekera, Head, Department of Forensic Medicine,
    University of Peradeniya, Sri Lanka.

    Prof. E. Astolfi, Professor of Toxicology, Facultad de Medicina,
    Universidad de Buenos Aires, Ajacucho 1337, Buenos Aires (1111),
    Argentina.

    Dr. I. Nir-Grosfeld, Hebrew University, Herdanah Medical School,
    Jerusalem, Israel.

    Prof. D.V.W. Parke, Head, Department of Biochemistry, University of
    Surrey, Guildford, Surrey, U.K.

    Dr. O.E. Paynter, U.S. Department of Commerce, Office of Environmental
    Affairs, Washington, D.C., U.S.A.

    Prof. A. Somogyi, Director, Department of Drugs, Animal Nutrition and
    Residue Research, Bundesgesundheitsamt, Thielallee 88-92, D-1000
    Berlin 33.


    FAO/WHO Secretariat

    Dr. R.L. Baron, Health Effects Research Laboratory, U.S. Environmental
    Protection Agency, Research Triangle Park, North Carolina 27711,
    U.S.A. (WHO Temporary Adviser).

    Mr. J.A.R. Bates, Pesticide Residues Specialist, Plant Protection
    Service, FAO, 00100 Rome, Italy (Secretary of FAO Panel of Experts on
    Pesticide Residues in Food and the Environment).

    Dr. J. Cabral, Unit of Chemical Carcinogenesis, International Agency
    for Research on Cancer, 150 Cours Albert-Thomas, 69372 Lyon Cedex 2,
    France (WHO Temporary Adviser).

    Mr. A.F. Machin, Senior Research Officer, Central Veterinary
    Laboratory, Ministry of Agriculture, Fisheries and Food, New Haw,
    Weybridge, Surrey KT15 3NB, U.K. (FAO Consultant).

    Dr. M. van Logten, National Institute of Public Health, Bilthoven,
    Netherlands (WHO Temporary Adviser).

    Dr. G. Vettorazzi, Toxicologist - Food, International Programs on
    Chemical Safety, Division of Environmental Health, WHO, 1211 Geneva
    27, Switzerland (Secretary of WHO Expert Group on Pesticide Residues).

    Others Attending

    Dr. L. Ladomery, Food Standards Officer, Joint FAO/WHO Food Standards
    Programme, FAO, Rome, Italy (Secretary of Codex Committee on Pesticide
    Residues).

    Mr. J. Wessel, International Programme on Chemical Safety, Division of
    Environmental Health, WHO, 1211 Geneva 27, Switzerland (WHO Temporary
    Adviser).

    Monographs edited by Mr. D.F. Lee and Dr. N.A. Smart (FAO Consultants)

    INTRODUCTION

    The report of the joint meeting of the FAO Panel of Experts on
    Pesticide Residues in Food and the Environment and the WHO Expert
    Group on Pesticide Residues held in Rome from 6 to 15 October 1980,
    contains a summary of the evaluations of residues in foods of the
    various pesticides considered at the session as well as information on
    the general principles followed by the meeting.  The present document
    contains summaries of the data considered, together with the
    recommendations made.

    The information included in the monographs has been obtained from the
    published literature wherever possible, but other sources have also
    been used.  Early and complete publications of the results of research
    in this field are very important, particularly those data which can
    form the basis for the estimation of acceptable daily intakes and
    appropriate residue levels.  Publication allows the research to be
    assessed by scientists from disciplines not necessarily represented at
    the meeting.  Data contained in unpublished reports is less
    satisfactory and, when considered, must be complete and
    nonconfidential and indicate authorship.

    Some of the compounds considered at this meeting have been previously
    evaluated and reported on in earlier publications.  Only new
    information is summarized in the relevant monographs and reference is
    made to the previously published evaluation(s) which should also be
    consulted.  Such monograph addenda are indicated by an asterisk in the
    "Contents" sheet.

    Annex 1 to this volume of monographs summarizes the recommendations on
    acceptable daily intakes, maximum residue limits and guideline levels
    made at the 1980 meeting. It has already appeared as an annex to the
    report of the meeting.

    NOTE

    Any comments on evaluation for acceptable daily intake should be
    addressed to:

    Food Safety Unit
    World Health Organization
    Geneva, Switzerland

    Any comments on residues in food and their evaluation should be
    addressed to:

    Pesticide Residues Specialist
    Plant Protection Service
    Plant Production and Protection Division
    Food and Agriculture Organization
    Rome, Italy





















    See Also:
       Toxicological Abbreviations