|WARFARIN||ICSC: 0821 (November 2010)|
| CAS #: 81-81-2
| UN #: 3027
|EC Number: 201-377-6
|ACUTE HAZARDS||PREVENTION||FIRE FIGHTING|
|FIRE & EXPLOSION||Combustible.||NO open flames. NO contact with strong oxidizing agents.||Use water spray, foam, powder, carbon dioxide.|
|AVOID ALL CONTACT! PREVENT DISPERSION OF DUST! IN ALL CASES CONSULT A DOCTOR!|
|Inhalation||Coughing up blood. Blood in the urine. Bleeding under the skin. Confusion. Symptoms may be delayed. See Notes.||Use closed system.||Refer for medical attention.|
|Skin||EASILY ABSORBED! See Inhalation.||Protective gloves. Protective clothing.||Remove contaminated clothes. See Notes. Rinse and then wash skin with water and soap. Refer immediately for medical attention .|
|Eyes||Wear face shield or eye protection in combination with breathing protection if powder.||Rinse with plenty of water (remove contact lenses if easily possible).|
|Ingestion||Diarrhoea. Nausea. Vomiting. Abdominal pain. Further see Inhalation.||Do not eat, drink, or smoke during work. Wash hands before eating.||Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer immediately for medical attention.|
|SPILLAGE DISPOSAL||CLASSIFICATION & LABELLING|
|Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.||
According to UN GHS Criteria
DANGERFatal if swallowed or if inhaled
Harmful in contact with skin
May damage fertility or the unborn child
Causes damage to blood system
Causes damage to blood system through prolonged or repeated exposure
Harmful to aquatic life
|Separated from strong oxidants and food and feedstuffs. Well closed. Store in an area without drain or sewer access.|
Put breakable packaging into closed unbreakable container.
Do not transport with food and feedstuffs.
|PHYSICAL & CHEMICAL INFORMATION|
Physical State; Appearance
|EXPOSURE & HEALTH EFFECTS|
Routes of exposure
Effects of short-term exposure
Effects of long-term or repeated exposure
|OCCUPATIONAL EXPOSURE LIMITS|
TLV: (inhalable fraction): 0.01 mg/m3, as TWA; (skin).
MAK: 0.02 mg/m3, 0.0016 ppm; peak limitation category: II(8); skin absorption (H); pregnancy risk group: B
|The substance is harmful to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to mammals. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal.|
|Warfarin is usually available commercially as the water soluble sodium salt (CAS 129-06-6). The physical properties above refer to the parent substance.
The symptoms of bleeding do not become manifest after one or two days.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Do NOT take working clothes home.
This CAS number is for the racemic mixture; other CAS numbers: 5543-57-7 (S-warfarin), 5543-58-8 (R-warfarin)
Symbol: T; R: 61-48/25-52/53; S: 53-45-61; Note: E
|All rights reserved. The published material is being distributed without warranty of any kind, either expressed or implied. Neither ILO nor WHO nor the European Commission shall be responsible for the interpretation and use of the information contained in this material.|
See Also: Toxicological Abbreviations Warfarin (HSG 96, 1995) Warfarin (PIM 563)