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Summary of Evaluations Performed by the
Joint FAO/WHO Expert Committee on Food Additives

TERTIARY BUTYLHYDROQUINONE
INS: 319
Chemical names: tert-BUTYLHYDROQUINONE; MONO-tert-BUTYLHYDROQUINONE; t-BUTYLHYDROQUINONE; 2-(1,1-DIMETHYLETHYL)-1,4-BENZENEDIOL
Synonyms: TBHQ
Functional class: ANTIOXIDANT
Latest evaluation: 1997
ADI: 0-0.7 mg/kg bw
Report: TRS 884-JECFA 49/11
Specifications: COMPENDIUM ADDENDUM 11/FNP 52 Add. 11/89 (METALS LIMITS) (2003)
Tox monograph: FAS 40-JECFA 49/3
Previous status: 1997, COMPENDIUM ADDENDUM 5/FNP 52 Add.5/193. R
1995, TRS 859-JECFA 44/8, COMPENDIUM ADDENDUM 3/FNP 52 Add.3/197, FAS 35-JECFA 44/87. 0-0.2 (TEMPORARY). TE. R
1990, TRS 806-JECFA 37/8, COMPENDIUM/1485. 0-0.2 (TEMPORARY). TE. R
1986, TRS 751-JECFA 30/17, FNP 37-JECFA 30/127, FAS 21-JECFA 30/47. 0-0.2 (TEMPORARY). TE. R
1977, TRS 617-JECFA 21/14, NMRS 57-JECFA 21/112. 0-0.5 (AS BHA, BHT, TBHQ, OR THE SUM OF THE THREE COMPOUNDS). FU. R
1975, NMRS 55/TRS 576-JECFA 19/16, FAS 8/NMRS 55A-JECFA 19/65. 0-0.75 (TEMPORARY). TE. S
1973, FNP 4-JECFA 17/237. N
Intake: 1998, TRS 891-JECFA 51/132,159; FAS 42-JECFA 51/453. Intake estimates based on food additive levels in the draft General Standard for Food Additives being developed by the Codex Committee on Food Additives and Contaminants, integrated with national data on food consumption, exceeded the ADI of 0-0.7 mg/kg bw for mean intake for the three Member States that submitted such data. In national data submitted by four Member States, estimates of mean intake of TBHQ did not exceed the ADI. The potential exists for consumers of high levels of TBHQ to exceed the ADI, but the available data were insufficient to estimate the number of such consumers or the magnitude and duration of intake above the ADI.
 
6 Feb 04    




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       Toxicological Abbreviations