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Summary of Evaluations Performed by the
Joint FAO/WHO Expert Committee on Food Additives

THIAMPHENICOL
Chemical names: D-d-THREO-2-DICHLOROACETAMIDO-1-(4-METHYLSULFONYLPHENYL)-1,3-PROPANEDIOL; D(+)-THREO-1-(4'-METHYLSULPHONYLPHENYL)-2-DICHLOROACETAMIDE PROPANE-1,3-DIOL; D-THREO-2,2-DICHLORO-N-beta-HYDROXY-a-(HYDROXYMETHYL)-p-(METHYLSULPHONYL)- PHENYL ACETAMIDE
Synonyms: DEXTROSULPHENIDOL; THIOPHENICOL
Functional class: VETERINARY DRUG (ANTIMICROBIAL AGENT)
Latest evaluation: 2002
ADI: 0-0.005 mg/kg bw (1999)
Comments/MRLs: The temporary MRLs in muscle, liver, kidney and fat of pigs, and in muscle of fish, were not extended because the information requested at the fifty-second meeting (1999) was not provided.
Report: TRS 911-JECFA 58/35
Residues: FNP 41/12-JECFA 52/119 (1999)
Tox monograph: FAS 43-JECFA 52/7 (1999)
Previous status: 1999, TRS 893-JECFA 52/28, FNP 41/12-JECFA 52/119, FAS 43-JECFA 52/7. 0-0.005 mg/kg bw. MLRs (TEMPORARY UNTIL 2002, EXPRESSED AS THE SUM OF THIAMPHENICOL AND ITS CONJUGATES, MEASURED AS THIAMPHENICOL): MUSCLE, LIVER, KIDNEY AND FAT (PIGS): 0.05 mg/kg; MUSCLE (FISH): 0.05 mg/kg. THE PREVIOUS TEMPORARY MRLs FOR CATTLE AND CHICKENS WERE WITHDRAWN AS THE DATA REQUIRED BY THE FORTY-SEVENTH MEETING (1999) WERE NOT PROVIDED. FU. TMRL
1996, TRS 876-JECFA 47/30, FNP 41/9-JECFA 47/89, FAS 38-JECFA 47/83. 0-0.006 (TEMPORARY). MRLs (TEMPORARY, EXPRESSED AS PARENT DRUG): MUSCLE, LIVER, KIDNEY AND FAT (CATTLE AND CHICKENS): 0.04. TE. TMRL
 
31 Jan 03    




    See Also:
       Toxicological Abbreviations
       Thiamphenicol (WHO Food Additives Series 38)