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Summary of Evaluations Performed by the
Joint FAO/WHO Expert Committee on Food Additives

BUTYLATED HYDROXYANISOLE
INS: 320
Chemical names: 3-TERTIARY-BUTYL-4-HYDROXYANISOLE; MIXTURE OF 3- AND 2-TERTIARY-BUTYL-4- HYDROXYANISOLE
Synonyms: BHA
Functional class: ANTIOXIDANT
Latest evaluation: 1988
ADI: 0-0.5 mg/kg bw
Report: TRS 776-JECFA 33/14
Specifications: COMPENDIUM ADDENDUM 11/FNP 52 Add. 11/89 (METALS LIMITS) (2003)
Tox monograph: FAS 24-JECFA 33/3
Previous status: 1988, FNP 38-JECFA 33/22; COMPENDIUM/249. R
1986, TRS 751-JECFA 30/12, FNP 37-JECFA 30/15, FAS 21-JECFA 30/3. 0-0.3 (TEMPORARY). TE. R
1983, TRS 696-JECFA 27/13, FNP 34-JECFA 29/25 (1985), FAS 18-JECFA 27/41. 0-0.5 (TEMPORARY; GROUP ADI, AS BHA, BHT AND TBHQ, SINGLY OR IN COMBINATION). TE. R (1985)
1983, TRS 696-JECFA 27/13, FNP 25-JECFA 26/55 (1982), FAS 18-JECFA 27/41. 0-0.5 (TEMPORARY; GROUP ADI, AS BHA, BHT AND TBHQ, SINGLY OR IN COMBINATION). TE. S
1982, TRS 683-JECFA 26/17, FNP 25-JECFA 26/55. 0-0.5 (TEMPORARY; GROUP ADI, AS BHA, BHT, TBHQ, SINGLY OR IN COMBINATION). TE. R
1980, TRS 653-JECFA 24/15, FNP 17-JECFA 24/17, FAS 15-JECFA 24/87. 0-0.5 (TEMPORARY; GROUP ADI AS BHA, BHT, TBHQ SINGLY OR IN COMBINATION). TE. R
1976, FNS 1/TRS 599-JECFA 20/11, NMRS 57-JECFA 21/25 (1977), FAS 10-JECFA 20/6. 0-0.5 (TEMPORARY; AS BHA, BHT, OR THE SUM OF THE TWO CHEMICALS). TE. R,T
1973, NMRS 53/TRS 539-JECFA 17/18, FNP 4-JECFA 17/188, FAS 5/NMRS 53A-JECFA 17/148. 0-0.5 (TEMPORARY; AS BHA, BHT, OR THE SUM OF BOTH). TE. R,T
1971, NMRS 50/TRS 488-JECFA 15/20, FAS 3/NMRS 50C-JECFA 15/52
1965, NMRS 40/TRS 339-JECFA 9/19. 0-0.5 (CONDITIONAL, O.5-2.0; AS SUM OF BUTYLATED HYDROXYTOLUENE AND BUTYLATED HYDROXYANISOLE). CO. S
1961, NMRS 31/TRS 228-JECFA 6/41, NMRS 31/TRS 228-JECFA 6/41. 0-0.5 (CONDITIONAL, 0.5-2.0). CO. S
1958, NMRS VOL I-III/73. N
Intake: 1998, TRS 891-JECFA 51/123,157; FAS 42-JECFA 51/415. Intake estimates based on food additive levels in the draft General Standard for Food Additives being developed by the Codex Committee on Food Additives and Contaminants, integrated with national data on food consumption, exceeded the ADI of 0-0.5 mg/kg bw in the three Member States that submitted such data. In national data submitted by seven Member States, estimates of mean intake of BHA did not exceed the ADI. The potential exists for consumers of high levels of BHA to exceed the ADI, but the available data were insufficient to estimate the number of such consumers or the magnitude and duration of intake above the ADI.
 
6 Feb 04    




    See Also:
       Toxicological Abbreviations
       Butylated hydroxyanisole (WHO Food Additives Series 5)
       Butylated hydroxyanisole (WHO Food Additives Series 10)
       Butylated hydroxyanisole (WHO Food Additives Series 21)
       Butylated hydroxyanisole (WHO Food Additives Series 24)