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Summary of Evaluations Performed by the
Joint FAO/WHO Expert Committee on Food Additives

EPRINOMECTIN
Chemical names: EPRINOMECTIN B1a:- (2AE,4E,5'S,8E,11R,13S,171R,20aR,20bS)-6'-[(S)-sec-BUTYL]-5',6,6'7,10,11,14,15,17a,20a,20b-DODECAHYDRO-20-,20b-DIHYDROXY-5',6,8,19-TETRAMETHYL-17-OXOSPIRO-[11,15,METHANO-2H,13H,17H-FURO[4,3,2-pq][2,6]BENZODIOXACYCLO-OCTADECIN-13,2'-[2H]PYRAN-7-YL-4-O-(4-ACETAMIDO-2,4,6-TRIDEOXY-3-O-METHYL-a-L-lyxo-HEXOPYRANOSYL)-2,6-DIDEOXY-3-O-METHYL-a-L-arabino-HEXANOPYRANOSIDE (IUPAC) (4"R)-4"-ACETYLAMINO)-5-O-DEMETHYL-4"-DEOXYAVERMECTIN A1a (CAS); EPRINOMECTIN B1b:- (2AE,4E,5'S,8E,11R,13S,171R,20aR, 20bS) - 5',6,6'7,10,11,14,15,17a,20,20a,20-DODECAHYDRO-2-,20b-DIHYDROXY-6'-ISOPROPYL-5',6,8,19-TETRAMETHYL-17-OXOSPIRO-[11,15,METHANO-2H,13H,17H-FURO[4,3,2-pq][2,6]BENZODIOXACYCLO-OCTADECIN-13,2'-[2H]PYRAN-7-YL-4-O-(4-ACETAMIDO-2,4,6-TRIDEOXY-3-O-METHYL-a-L-lyxo-HEXOPYRANOSYL)-2,6-DIDEOXY-3-O-METHYL-a-L-arabino-HEXANOPYRANOSIDE (IUPAC) (4"R)-4"-ACETYLAMINO)-5-O-DEMETHYL-25-DE-(1-METHYL-PROPYL)-4"-DEOXY-25-(1-METHYLETHYL)AVERMECTIN A1a (CAS)
Functional class: VETERINARY DRUG (ANTHELMINTHIC AGENT)
Latest evaluation: 1998
ADI: 0-0.01 mg/kg bw
Comments/MRLs: MRLs (expressed as eprinomectin B1a, in mg/kg tissue, mg/l milk): Muscle (cattle): 0.1; Liver (cattle): 2; Kidney (cattle): 0.3; Fat (cattle): 0.25; Milk (cattle): 0.02
Report: TRS 888-JECFA 50/4
Residues: FNP 41/11-JECFA 50/31
Tox monograph: FAS 41-JECFA 50/3
 
12 Nov 01    




    See Also:
       Toxicological Abbreviations
       Eprinomectin (WHO Food Additives Series 41)