PESTICIDE RESIDUES IN FOOD - 1982
Sponsored jointly by FAO and WHO
EVALUATIONS 1982
Data and recommendations of the joint meeting
of the FAO Panel of Experts on Pesticide Residues
in Food and the Environment and the
WHO Expert Group on Pesticide Residues
Rome, 23 November - 2 December 1982
Food and Agriculture Organization of the United Nations
Rome 1983
The designations employed and the presentation of material in this
publication do not imply the expression of any opinion whatsoever on
the part of the Food and Agriculture Organization of the United
Nations concerning the legal status of any country, city or area or of
its authorities, or concerning the delimitation of its frontiers or
boundaries.
M-84
ISBN 92-5 101432-9
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reproduction, should be addressed to the Director, Publications
Division, Food and Agriculture Organization of the United Nations, Via
delle Terme di Caracalla, 00100 Rome, Italy.
(c) FAO 1983
CONTENTS
List of Those Attending the Meeting
Introduction
The Monographs
Acephate*
WHO - Toxicology
Aldicarb*
WHO - Toxicology
FAO - Residues
Azocyclotin/Cyhexatin*
FAO - Residues
Bendiocarb
WHO - Toxicology
FAO - Residues
Bromophos*
FAO - Residues
Captan*
WHO - Toxicology
Chlordane*
WHO - Toxicology
Chlorpyrifos*
WHO - Toxicology
FAO - Residues
Cyanofenphos*
FAO - Residues
Cypermethrin*
FAO - Residues
Deltamethrin*
WHO - Toxicology
FAO - Residues
Dichlofluanid*
FAO - Residues
* Addendum
Diphenylamine*
WHO - Toxicology
Endosulfan*
WHO - Toxicology
Ethiofencarb*
WHO - Toxicology
FAO - Residues
Ethion*
WHO - Toxicology
Etrimfos*
WHO - Toxicology
Fenitrothion*
WHO - Toxicology
Fensulfothion*
WHO - Toxicology
Isofenphos*
WHO - Toxicology
FAO - Residues
Metalaxyl
WHO - Toxicology
FAO - Residues
Methacrifos*
WHO - Toxicology
Methamidophos*
WHO - Toxicology
Paraquat*
WHO - Toxicology
Parathion Methyl*
WHO - Toxicology
Permethrin*
FAO - Residues
Phorate*
WHO - Toxicology
* Addendum
Phosphamidon*
WHO - Toxicology
Phoxim
WHO - Toxicology
Pirimicarb*
WHO - Toxicology
Propargite*
WHO - Toxicology
FAO - Residues
Triazophos
WHO - Toxicology
Vamidothion*
WHO - Toxicology
Annex I - Acceptable Daily Intakes, Maximum Residue Limits and
Guideline Levels Proposed at the 1982 Meeting
Annex II - Previous FAO and WHO Documentation
* Addendum
1982 JOINT MEETING OF THE FAO PANEL OF EXPERTS ON PESTICIDE RESIDUES
IN FOOD AND THE ENVIRONMENT AND THE WHO EXPERT GROUP ON PESTICIDE
RESIDUES
Rome, 22 November - 1 December 1982
FAO Panel of Experts on Pesticide Residues in Food and the Environment
A. Ambrus, Plant Protection and Agrochemistry Centre, Budapest,
Hungary
J.A.R. Bates, Pesticide Registration Department, Ministry of
Agriculture, Fisheries and Food, Hatching Green, Harpenden, Herts, UK
(Rapporteur)
K.R. Hill, Analytical Chemistry Laboratory, US Department of
Agriculture, Agricultural Environment Quality Institute, Beltsville,
Md, USA (Chairman)
N.F. Ives, Office of Pesticide Programs, Environmental Protection
Agency, Washington, DC, USA
M.A. Martinez, Department of Pesticides, Dirección/General, Sanidad
Vegetal, Mexico City, Mexico
K. Voldum-Clausen, Division of Pesticides and Contaminants, National
Food Institute, Soborg, Denmark
Observer invited by FAO
A.J. Pieters, Directorate of Public Health, Foodstuffs Division,
Leidschendam, Netherlands (Chairman of the Codex Committee on
Pesticide Residues)
WHO Expert Group on Pesticide Residues
C. Amerasekere, Department of Forensic Medicine, University of
Peradeniya, Peradeniya, Sri Lanka
D. Clegg, Pesticide Section, Toxicological Evaluation Division,
National Health and Welfare, Ottawa, Canada (Vice-Chairman)
D. de Paola, Department of Pathology, University Hospital, Rio de
Janeiro, Brazil
D.V. Parke, Department of Biochemistry, University of Surrey,
Guildford, England
O.E. Paynter, US Department of Commerce, Washington, DC, USA
R. Plestina, Institute for Medical Research and Occupational Health,
Zagreb, Yugoslavia
FAO/WHO Secretariat
A. Adam, Plant Protection Service, FAO, Rome, Italy (Secretary of the
FAO Panel of Experts on Pesticide Residues in Food and the
Environment)
A.L. Black, Commonwealth Department of Health, Woden, Australia (WHO
Temporary Adviser)
J.R. Cabral, Unit of Chemical Carcinogenesis, International Agency for
Research on Cancer, Lyon, France
A. Di Muccio, Toxicological Laboratory, Instituto Superiore de Sanità,
Rome, Italy (WHO Temporary Adviser)
R.B. Jaeger, US Environmental Protection Agency, Washington, DC, USA
(WHO Temporary Adviser)
A.F. Machin, Central Veterinary Laboratory, Ministry of Agriculture,
Fisheries and Food, Weybridge, Surrey, UK (FAO Consultant)
T. Pekkanen, Department of Food Hygiene, College of Veterinary
Medicine, Helsinki, Finland (WHO Temporary Adviser)
R. Read, International Programme on Chemical Safety, Division of
Environmental Health, WHO, Geneva, Switzerland
A.G. Rico, Laboratoire de Radioélements et d'Etudes Métaboliques,
Ecole Nationale Vétérinaire, Toulouse, France (WHO Temporary Adviser)
M. Tobe, Division of Toxicology, Biological Research Centre, National
Institute of Hygienic Sciences, Tokyo, Japan (WHO Temporary Adviser)
G. Vettorazzi, International Programme on Chemical Safety, Division of
Environmental Health, WHO, Geneva, Switzerland (Secretary of the WHO
Expert Group on Pesticide Residues)
E. Weisenberg, Institute for the Standardization and Control of
Pharmaceuticals, Ministry of Health, Jerusalem, Israel (WHO Temporary
Adviser)
D. Wu-Lau, Pesticide Section, National Health and Welfare, Ottawa,
Canada, (WHO Temporary Adviser)
K. Zammarano, Plant Protection Service, FAO, Rome, Italy (Monographs
Editor)
INTRODUCTION
The report of the Joint Meeting of the FAO Panel of Experts on
Pesticide Residues in Food and the Environment and the WHO Expert
Group on Pesticide Residues, held in Rome from 22 November - 1
December 1982, contains a summary of the evaluations of residues in
foods of the various pesticides considered at the session as well as
information on the general principles followed by the Meeting. The
present document contains summaries of the data considered, together
with the recommendations made.
The information included in the monographs has been obtained from
the published literature wherever possible, but other sources have
also been used. Early and complete publication of the results of
research in this field are very important, particularly those data
which can form the basis for the estimation of acceptable daily
intakes and appropriate residue levels. Publication allows the
research to be assessed by scientists from disciplines not necessarily
represented at the meeting. Data contained in unpublished reports is
less satisfactory and, when considered, must be complete and
nonconfidential and indicate authorship.
Some of the compounds considered at this Meeting have been
previously evaluated and reported on in earlier publications. Only new
information is summarized in the relevant monographs and reference is
made to the previously published evaluation(s), which should also be
consulted. Such monograph addenda are indicated by an asterisk in the
"Contents" sheet.
Annex 1 to this volume of monographs summarizes the
recommendations on acceptable daily intakes, maximum residue limits
and guideline levels made at the 1982 Meeting. It has already appeared
as an annex to the report of the Meeting.
NOTE
Any comments on evaluation for acceptable daily intake should be
addressed to:
Food Safety Unit
World Health Organization
Geneva, Switzerland
Any comments on residues in food and their evaluation should be
addressed to:
Pesticide Residues Specialist
Plant Protection Service
Plant Production and Protection Division
Food and Agriculture Organization
Rome, Italy