International Agency for Research on Cancer (IARC) - Summaries & Evaluations
DIBENZ[a,h]ACRIDINE
VOL.: 32 (1983) (p. 277)
CAS No.: 226-36-8
Chem. Abstr. Name: Dibenz(a,h)acridine
5. Summary of Data Reported and Evaluation
5.1 Experimental data
Dibenz[a,h]acridine has been shown to be carcinogenic to
experimental animals.
No data on the teratogenicity of this compound were available.
Both positive and negative results were obtained in tests of
mutagenicity in Salmonella typhimurium.
There is inadequate evidence that dibenz[a,h]acridine is active
in short-term tests.
5.2 Human data
Dibenz[a,h]acridine is present as a minor component of the total
content of polynuclear aromatic compounds in tobacco smoke and urban
pollutants.
5.3 Evaluation
There is sufficient evidence that dibenz[a,h]acridine is
carcinogenic to experimental animals.
For definition of the italicized terms, see Preamble Evaluation.
Previous evaluation: Vol. 3 (1973)
Subsequent evaluation: Suppl. 7 (1987) (p. 61: Group 2B)
Synonyms
- 7-Azadibenz(a,h)anthracene
- DB(a,h)AC
- 1,2:5,6-Dibenzacridine
- 1,2,5,6-Dibenzacridine
- Dibenz(a,d)acridine
- 1,2,5,6-Dibenzoacridine
- 1,2,5,6-Dinaphthacridine
Last updated: 17 April 1998