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TRICHLOROETHYLENE
ICSC: 0081
Peer-Review Status: 12.04.2013 Validated
1,1,2-Trichloroethylene
Trichloroethene
Ethylene trichloride
Acetylene trichloride
Tri
Chlorylen
TCE
Trilene
Trichlo 
CAS #: 79-01-6 RTECS #: KX4550000
UN #: 1710
EC #: 602-027-00-9
EINECS #: 201-167-4
    Formula: C2HCl3 / ClCH=CCl2
Molecular mass: 131.4

TYPES OF HAZARD
/ EXPOSURE
ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE-FIGHTING
FIRE Combustible under specific conditions. See Notes. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking. NO contact with hot surfaces, strong bases or finely divided metals.  In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION   Prevent build-up of electrostatic charges (e.g., by grounding).  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   PREVENT GENERATION OF MISTS! AVOID ALL CONTACT!   
Inhalation Dizziness. Drowsiness. Headache. Weakness. Nausea. Unconciousness.  Use closed system.  Fresh air, rest. Artificial respiration may be needed. Refer immediately for medical attention. 
Skin Dry skin. Redness.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes Redness. Pain.  Wear safety spectacles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Sore throat. Aspiration hazard! See Inhalation. Cardiac dysrhythmia. Respiratory arrest.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Refer immediately for medical attention. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance and complete protective clothing. Ventilation. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs.
Marine pollutant. 
EC Classification
Symbol: T; R: 45-36/38-52/53-67; S: 53-45-61 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 
GHS Classification
Signal: Danger
May be harmful if swallowed
Causes skin irritation
Causes serious eye irritation
Suspected of causing genetic defects
May cause cancer
May cause drowsiness or dizziness
May be harmful if swallowed and enters airways
Harmful to aquatic life with long lasting effects 
excl mark;warncancer;health haz

EMERGENCY RESPONSE SAFE STORAGE
NFPA Code: H2; F1; R0.  Separated from metals, strong bases, food and feedstuffs, combustible substances and ignition sources. See Chemical Dangers. Dry. Keep in the dark. Keep in a well-ventilated room. Cool. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air. As a result of flow, agitation, etc., electrostatic charges can be generated. 

Chemical dangers
Decomposes on contact with hot surfaces or flames. This produces toxic and corrosive fumes of phosgene and hydrogen chloride. Decomposes on contact with strong alkali. This produces dichloroacetylene. This increases fire hazard. Reacts violently with finely divided metals. This generates fire and explosion hazard. Slowly decomposed by light in the presence of moisture. This produces corrosive hydrochloric acid. 

Occupational exposure limits
TLV: 10 ppm, 54 mg/m³ as TWA; 25 ppm, 135 mg/m³ as STEL; A2 (suspected human carcinogen); BEI issued; (ACGIH 2008).
MAK: Carcinogen category: 1; Germ cell mutagen group: 3B; Skin absorption (H); (DFG 2007).
EU OEL ( selected): 10 ppm, 54.7 mg/m³ as TWA; 30 ppm, 164.1 mg/m³ as STEL; SCOEL recommendation available. 

Routes of exposure
The substance can be absorbed into the body by inhalation, by ingestion and through the skin. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. If swallowed the substance may cause vomiting and could result in aspiration pneumonitis. The substance may cause effects on the central nervous system, liver and kidneys. This may result in impaired functions. Exposure at high concentrations could cause unconsciousness. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the central nervous system. This may result in fatigue, irritability and mental and memory disturbances. The substance may have effects on the liver, kidneys and immune system. This substance is carcinogenic to humans. Causes toxicity to human reproduction or development. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 87°C
Melting point: -86 to -88°C
Relative density (water = 1): 1.5 (20°C)
Solubility in water, g/100ml at 20°C: 0.1
Vapour pressure, kPa at 20°C: 7.8
Relative vapour density (air = 1): 4.5
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.3
Auto-ignition temperature: 410°C
Explosive limits, vol% in air: 7.9 - 100
Octanol/water partition coefficient as log Pow: 2.42
Electrical conductivity: 800 pS/m  
The substance is harmful to aquatic organisms. The substance may cause long-term effects in the aquatic environment. It is strongly advised not to let the chemical enter into the environment. 

NOTES
Combustible vapour/air mixtures difficult to ignite, may be developed under certain conditions.
Use of alcoholic beverages enhances the harmful effect.
Depending on the degree of exposure, periodic medical examination is suggested.
The odour warning when the exposure limit value is exceeded is insufficient.
Do NOT use in the vicinity of a fire or a hot surface, or during welding. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Trichloroethylene (EHC 50, 1985)
       Trichloroethylene (WHO Food Additives Series 10)
       TRICHLOROETHYLENE (JECFA Evaluation)
       Trichloroethylene (FAO/PL:1968/M/9/1)
       Trichloroethylene (IARC Summary & Evaluation, Volume 63, 1995)