International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 3 (1973) (p. 137)

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

The data are confined to two skin painting experiments in mice in which benzo(e)pyrene evoked a weaker response than either benzo(a)pyrene or dibenz(a,h)anthracene. Benzo(e)pyrene does not appear to be an initiator of skin carcinogenesis in mice. It has not been tested by other routes in the mouse or in other species.

5.2 Human carcinogenicity data

No case reports or epidemiological studies on the significance of benzo(e)pyrene exposure to man are available. However, coal-tar and other materials which are known to be carcinogenic to man may contain benzo(e)pyrene. The substance has also been detected in other environmental situations. The possible contribution of polycyclic aromatic hydrocarbons from some environmental sources to the overall carcinogenic risk to man is discussed in the General Remarks.

Subsequent evaluations: Vol. 32 (1983); Suppl. 7 (1987) (p. 58: Group 3)

For definition of Groups, see Preamble Evaluation.

Last updated: 16 March 1998

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