International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 4 (1974) (p. 197)

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

N-Nitroso-di-n-butylamine (DBNA) is carcinogenic in all animal species tested: mouse, rat, hamster and guinea pig. It is carcinogenic by oral and other routes, and it is particularly effective as a bladder carcinogen after subcutaneous injection. It is carcinogenic after exposure to a single dose.

5.2 Human carcinogenicity data

No epidemiological data are available to the Working Group.

Subsequent evaluations: Vol. 17 (1978); Suppl. 7 (1987) (p. 67: Group 2B)

For definition of Groups, see Preamble Evaluation.

Last updated: 17 March 1998

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       Toxicological Abbreviations