International Agency for Research on Cancer (IARC) - Summaries & Evaluations
N-NITROSO-N-METHYLURETHANE
VOL.: 4 (1974) (p. 211)
CAS No.: 615-53-2
5. Summary of Data Reported and Evaluation
5.1 Animal carcinogenicity data
N-Nitroso-N-methylurethane is carcinogenic in all species
tested: mouse, rat, hamster, guinea-pig. It has a local as well as a
systemic carcinogenic effect, producing tumours at different sites by
oral and other routes of administration. It is carcinogenic in
single-dose experiments and following pre-natal exposure.
5.2 Human carcinogenicity data
No epidemiological data are available to the Working Group.
Subsequent evaluation: Suppl. 7 (1987) (p. 66: Group 2B)
For definition of Groups, see Preamble Evaluation.
Synonyms
- Ethyl ester of methylnitroso-carbamic acid
- N-Methyl-N-nitroso-ethylcarbamate
- N-Methyl-N-nitrosourethan
- MNUN
- NMUT
Last updated: 17 March 1998