International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 4 (1974) (p. 211)

CAS No.: 615-53-2

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

N-Nitroso-N-methylurethane is carcinogenic in all species tested: mouse, rat, hamster, guinea-pig. It has a local as well as a systemic carcinogenic effect, producing tumours at different sites by oral and other routes of administration. It is carcinogenic in single-dose experiments and following pre-natal exposure.

5.2 Human carcinogenicity data

No epidemiological data are available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 66: Group 2B)

For definition of Groups, see Preamble Evaluation.


Last updated: 17 March 1998

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       Toxicological Abbreviations