International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 5 (1974) (p. 211)

CAS No.: 82-68-8
Chem. Abstr. Name: Pentachloronitrobenzene

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Quintozene (pentachloronitrobenzene) was tested in a preliminary study by the oral route in two strains of mice and produced an increased incidence of hepatomas in males of one strain. A feeding study in rats was considered inadequate. Application of quintozene followed by croton oil to mouse skin gave positive results which could not be interpreted due to a lack of adequate controls.

5.2 Human carcinogenicity data

No epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 71: Group 3)

For definition of Groups, see Preamble Evaluation.


Last updated: 17 March 1998

    See Also:
       Toxicological Abbreviations