International Agency for Research on Cancer (IARC) - Summaries & Evaluations
2-(2-FORMYLHYDRAZINO)-4-(5-NITRO-2-FURYL)THIAZOLE
VOL.: 7 (1974) (p. 151)
CAS No.: 3570-75-0
5. Summary of Data Reported and Evaluation
5.1 Animal carcinogenicity data
2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole is carcinogenic in
mice, rats and hamsters following oral administration, the only
species and route tested. In mice it produced mainly stomach and
pulmonary tumours and lymphocytic leukaemias. In rats it produced
mainly mammary, renal, hepatic and gastrointestinal tract tumours and
lymphocytic leukaemias; in hamsters it produced mainly forestomach and
urinary bladder tumours.
5.2 Human carcinogenicity data
No case reports or epidemiological studies were available to the
Working Group.
Subsequent evaluation: Suppl. 7 (1987) (p. 63: Group 2B)
For definition of Groups, see Preamble Evaluation.
Synonyms
- AS-17665
- FNT
- Formic acid 2-[4-(5-nitro-2-furyl)-2-thiazolyl]hydrazide
- 2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazol
- Nefurthiazole
- Nifurthiazol
- Nifurthiazole
Last updated: 19 March 1998