International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 7 (1974) (p. 67)

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Propylthiouracil produced thyroid tumours in mice, rats, hamsters, and guinea-pigs following oral administration, the only route tested. In mice, pituitary adenomas were also observed.

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluations: Suppl. 7 (1987); Vol. 79 (2001)

Last updated: 20 March 1998

    See Also:
       Toxicological Abbreviations
       Propylthiouracil  (IARC Summary & Evaluation, Supplement7, 1987)
       Propylthiouracil  (IARC Summary & Evaluation, Volume 79, 2001)