International Agency for Research on Cancer (IARC) - Summaries & Evaluations
CITRUS RED No. 2
VOL.: 8 (1975) (p. 101)
CAS No.: 6358-53-8
Chem. Abstr. Name: 1-[(2,5-Dimethoxyphenyl)azo]-2-naphthalenol
5. Summary of Data Reported and Evaluation
5.1 Animal carcinogenicity data
Citrus red No. 2 is carcinogenic in mice and rats. Following its oral
administration it produced hyperplasia and tumours of the bladder.
Given subcutaneously, it produced adenocarcinomas of the lung and
lymphosarcomas in female mice. Its administration in mice by bladder
implantation produced carcinomas of that organ.
5.2 Human carcinogenicity data
No case reports or epidemiological studies were available to the
Subsequent evaluation: Suppl. 7 (1987) (p. 60: Group 2B)
For definition of Groups, see Preamble Evaluation.
- C.I. Solvent red 80
- Citrus red 2
Last updated: 23 March 1998