International Agency for Research on Cancer (IARC) - Summaries & Evaluations
ortho-AMINOAZOTOLUENE
VOL.: 8 (1975) (p. 61)
CAS No.: 97-56-3
Chem. Abstr. Name: 2-Methyl-4 [(2-methylphenyl)azo]-benzenamine
5. Summary of Data Reported and Evaluation
5.1 Animal carcinogenicity data
ortho-Aminoazotoluene is carcinogenic in mice, rats, hamsters and dogs
following its oral administration, producing mainly tumours of the
liver, gall-bladder, lung and urinary bladder. It also produced a
carcinogenic effect following its administration by other routes in
mice and rats. There is some evidence that it produces papillomas
of the bladder in rabbits following its administration by direct
bladder instillation and in mice after bladder implantation. It is
effective in single doses in newborn mice.
5.2 Human carcinogenicity data
No case reports or epidemiological studies were available to the
Working Group.
Subsequent evaluation: Suppl. 7 (1987) (p. 56: Group 2B)
For definition of Groups, see Preamble Evaluation.
Synonyms
- AAT
- Aminoazotoluene
- 2-Amino-5-azotoluene
- Brasilazina Oil Yellow R
- C.I. Solvent Yellow 3
- Fast Garnet GBC base
- Fast Oil Yellow
- Fast Spirit Yellow
- Fast Yellow AT
- Fat Yellow B
- Hidaco oil Yellow
- OAAT
- Organol Yellow 2T
- Somalia Yellow R
- Toluazotoluidine
- Tulabase Fast Garnet GB
- Waxakol Yellow NL
Last updated: 19 March 1998