International Agency for Research on Cancer (IARC) - Summaries & Evaluations
BIS(2-CHLOROETHYL)ETHER
VOL.: 9 (1975) (p. 117)
CAS No.: 111-44-4
Chem. Abstr. Name: 1,1'-Oxybis(2-chloro)ethane
5. Summary of Data Reported and Evaluation
5.1 Animal carcinogenicity data
Bis(2-chloroethyl)ether produced an increased incidence of liver-cell
tumours in male mice of two strains following its oral administration.
Its administration by the subcutaneous route in mice produced a low
incidence of sarcomas at the injection site.
5.2 Human carcinogenicity data
No case reports or epidemiological studies were available to the
Working Group.
Subsequent evaluation: Vol. 71 (1999)
For definition of Groups, see Preamble Evaluation.
Synonyms
- Bis(chloroethyl)ether
- Bis(b-chloroethyl)ether
- Chlorex
- 1-Chloro-2-(b-chloroethoxy)ethane
- DCEE
- 2,2'-Dichlorodiethyl ether
- b,b'-Dichlorodiethyl ether
- Dichloroether
- Dichloroethyl ether
- 2,2'-Dichloroethyl ether
- b,b'-Dichloroethyl ether
- Di-2-chloroethyl ether
- Di(2-chloroethyl)ether
- Di(b-chloroethyl)ether
- Dichloroethyl oxide
- sym-Dichloroethyl ether
Last updated: 13 April 1999