International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 9 (1975) (p. 117)

CAS No.: 111-44-4
Chem. Abstr. Name: 1,1'-Oxybis(2-chloro)ethane

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Bis(2-chloroethyl)ether produced an increased incidence of liver-cell tumours in male mice of two strains following its oral administration. Its administration by the subcutaneous route in mice produced a low incidence of sarcomas at the injection site.

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Vol. 71 (1999)

For definition of Groups, see Preamble Evaluation.


Last updated: 13 April 1999

    See Also:
       Toxicological Abbreviations
       Bis(2-chloroethyl)ether  (IARC Summary & Evaluation, Volume 71, 1999)