International Agency for Research on Cancer (IARC) - Summaries & Evaluations
LUTEOSKYRIN
VOL.: 10 (1976) (p. 163)
CAS No.: 21884-44-6
Chem. Abstr. Name: (1b, 1'b,
3b, 3'b) 8,8'-Dihydroxy-rugulosin
5. Summary of Data Reported and Evaluation
5.1 Animal carcinogenicity data
Luteoskyrin is carcinogenic in mice following its oral administration,
the only species and route of administration tested; it produced
benign and malignant tumours of the liver.
5.2 Human carcinogenicity data
No case reports or epidemiological studies were available to the
Working Group.
Subsequent evaluation: Suppl. 7 (1987) (p. 65: Group 3)
For definition of Groups, see Preamble Evaluation.
Synonyms
- Flavomycelin
- Stereoisomer of 1,4,7,9,12,15,17,20-octahydroxy-3,11-dimethyl-5H,6H-
6,13a,5a,14-1,2,3,4-butanetetraylcycloocta[1,2-b:5,6-b']dinaphthalene-
5,8,13,16(14H)-tetrone
- 2,2',3,3'-Tetrahydro-2,2',4,4',5,5',8,8'-octahydroxy-7,7'-dimethyl-(1,1'-bianthracene)-
9,9',10,10'-tetrone
Last updated: 22 March 1998