beta-Butyrolactone (IARC Summary & Evaluation, Volume 11, 1976)

International Agency for Research on Cancer (IARC) - Summaries & Evaluations

b-BUTYROLACTONE

VOL.: 11 (1976) (p. 225)

CAS No.: 3068-88-0
Chem. Abstr. Name: 4-Methyl-2-oxetanone

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

b-Butyrolactone is carcinogenic in mice by skin application and by subcutaneous injection and in rats by oral administration and by subcutaneous injection. It produced tumours at the site of administration in both species.

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Vol. 71 (1999)

Synonyms

3-Hydroxybutanoic acid, b-lactone
3-Hydroxybutyric acid lactone
3-Hydroxybutyric acid, b-lactone

Last updated: 13 April 1999





























    See Also:
       Toxicological Abbreviations
       Butyrolactone, beta-  (IARC Summary & Evaluation, Volume 71, 1999)