Dulcin (IARC Summary & Evaluation, Volume 12, 1976)

International Agency for Research on Cancer (IARC) - Summaries & Evaluations

DULCIN

VOL.: 12 (1976) (p. 97)

CAS No.: 150-69-6
Chem. Abstr. Name: (4-Ethoxyphenyl) urea

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Dulcin has been tested only in rats in oral administration. Increased incidences of liver-cell adenomas were observed in one study, and papillomas of the renal pelvis and bladder, associated with stone formation, were seen in another study, but these results were not confirmed in two other trials. No evaluation of the carcinogenicity of dulcin can be made.

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 63: Group 3)

For definition of Groups, see Preamble Evaluation.

Synonyms

Dulcine
para-Ethoxyphenylurea
para-Phenetolcarbamide
para-Phenetolecarbamide
para-Phenetylurea
Sucrol
Valzin

Last updated: 25 March 1998





























    See Also:
       Toxicological Abbreviations
       DULCIN (JECFA Evaluation)