International Agency for Research on Cancer (IARC) - Summaries & Evaluations
ZECTRAN
VOL.: 12 (1976) (p. 237)
CAS No.: 315-18-4
Chem. Abstr. Name: 4-(Dimethylamino)-3,5-dimethylphenol methylcarbamate (ester)
5. Summary of Data Reported and Evaluation
5.1 Animal carcinogenicity data
Zectran has been tested by oral administration and by single
subcutaneous injection in two strains of mice. Following its oral
administration, an increased incidence of lung adenomas was observed
in both sexes of one strain combined, together with a slight increase
in the number of liver-cell tumours in males of the same strain. The
available data do not allow an evaluation of the carcinogenicity of
zectran to be made.
5.2 Human carcinogenicity data
No case reports or epidemiological studies were available to the
Working Group.
Subsequent evaluation: Suppl. 7 (1987) (p. 74: Group 3)
For definition of Groups, see Preamble Evaluation.
Synonyms
- 4-(Dimethylamino)-3,5-dimethylphenol, methylcarbamate
- 4-Dimethylamino-3,5-dimethylphenyl N-methylcarbamate
- 4-(Dimethylamino)-3,5-xylenol, methylcarbamate (ester)
- 4-Dimethylamino-3,5-xylyl methylcarbamate
- 4-Dimethylamino-3,5-xylyl N-methylcarbamate
- Dowco 139
- ENT 25,766
- Methylcarbamic acid, 4-(dimethylamino)-3,5-xylyl ester
- Methyl-4-dimethylamino-3,5-xylyl carbamate
- Methyl-4-dimethylamino-3,5-xylyl ester of carbamic acid
- Mexacarbate
- Mexicarbate
- Zactran
- Zectane
- Zextran
Last updated: 25 March 1998