International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 12 (1976) (p. 237)

CAS No.: 315-18-4
Chem. Abstr. Name: 4-(Dimethylamino)-3,5-dimethylphenol methylcarbamate (ester)

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Zectran has been tested by oral administration and by single subcutaneous injection in two strains of mice. Following its oral administration, an increased incidence of lung adenomas was observed in both sexes of one strain combined, together with a slight increase in the number of liver-cell tumours in males of the same strain. The available data do not allow an evaluation of the carcinogenicity of zectran to be made.

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 74: Group 3)

For definition of Groups, see Preamble Evaluation.


Last updated: 25 March 1998

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