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International Agency for Research on Cancer (IARC) - Summaries & Evaluations

METRONIDAZOLE

VOL.: 13 (1977) (p. 113)

5. Summary of Data Reported and Evaluation

5.1 Animal data

Metronidazole is carcinogenic in mice after its oral administration: it significantly increased the incidence of lung tumours in both sexes and the incidence of lymphomas in females. Its oral administration to rats increased the incidence and multiplicity of mammary fibroadenomas.

5.2 Human data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987)

Last updated: 25 March 1998 






























    See Also:
       Toxicological Abbreviations
       METRONIDAZOLE (JECFA Evaluation)
       Metronidazole (PIM 347)
       Metronidazole  (IARC Summary & Evaluation, Supplement7, 1987)