VOL.: 15 (1977) (p. 223)
Isopropyl oils formed during the strong-acid process for synthesis of isopropyl alcohol were tested in mice by skin application, inhalation exposure and subcutaneous injection, and isopropyl oils formed during the weak-acid process were tested in mice by skin application and subcutaneous injection. Although an increased incidence of lung tumours was observed following inhalation or subcutaneous injection of isopropyl oils formed during the strong-acid process, all of these studies had some limitations due to short duration or incomplete reporting and to the unknown or variable composition of the materials tested. The available data thus do not provide sufficient evidence on which to base an evaluation of the carcinogenicity of isopropyl oils in experimental animals.
Subsequent evaluation: Suppl. 7 (1987); Vol. 71 (1999)
See Also: Toxicological Abbreviations