International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 15 (1977) (p. 149)

CAS No.: 110-57-6
Chem. Abstr. Name: (E)-1,4-Dichloro-2-butene

5. Summary of Data Reported and Evaluation

5.1 Animal data

trans-1,4-Dichlorobutene has been tested in female mice by skin application and by subcutaneous and intraperitoneal injection. When injected subcutaneously or intraperitoneally, it produced low incidences of local sarcomas. The available data do not allow an evaluation of the carcinogenicity of this compound to be made.

5.2 Human data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Vol. 71 (1999)

For definition of Groups, see Preamble Evaluation.

Last updated: 13 April 1999

    See Also:
       Toxicological Abbreviations
       trans-1,4-Dichlorobutene  (IARC Summary & Evaluation, Volume 71, 1999)