1,2,3-Tris(chloromethoxy)propane (IARC Summary & Evaluation, Volume 15, 1977)

International Agency for Research on Cancer (IARC) - Summaries & Evaluations

1,2,3-TRIS(CHLOROMETHOXY)PROPANE

VOL.: 15 (1977) (p. 301)

CAS No.: 38571-73-2

5. Summary of Data Reported and Evaluation

5.1 Animal data

1,2,3-Tris(chloromethoxy)propane is carcinogenic in mice, the only species tested, following its subcutaneous or intraperitoneal administration; it produced malignant tumours at the sites of administration. Skin papillomas and a low incidence of skin carcinomas were observed in skin-painting studies in mice.

5.2 Human data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Vol. 71 (1999)

Synonyms

Glycerol[tri(chloromethyl)]ether
Tris-1,2,3-(chloromethoxy) propane

Last updated: 13 April 1999





























    See Also:
       Toxicological Abbreviations
       1,2,3-Tris(chloromethoxy)propane  (IARC Summary & Evaluation, Volume 71, 1999)