International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 16 (1978) (p. 319)

CAS No.: 602-87-9
Chem. Abstr. Name: 1,2-Dihydro-5-nitroacenaphthylene

5. Summary of Data Reported and Evaluation

5.1 Animal data

5-Nitroacenaphthene is carcinogenic in female rats and female hamsters following its oral administration; it produced mainly adenocarcinomas of the small intestine and mammary carcinomas in female but not in male rats and cholangiomas in female but not in male hamsters. In addition, it produced leukaemia and reticulum-cell sarcomas in mice following its intraperitoneal injection.

5.2 Human data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 67: Group 2B)

For definition of Groups, see Preamble Evaluation.


Last updated: 26 March 1998

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