International Agency for Research on Cancer (IARC) - Summaries & Evaluations
5-NITROACENAPHTHENE
VOL.: 16 (1978) (p. 319)
CAS No.: 602-87-9
Chem. Abstr. Name: 1,2-Dihydro-5-nitroacenaphthylene
5. Summary of Data Reported and Evaluation
5.1 Animal data
5-Nitroacenaphthene is carcinogenic in female rats and female hamsters
following its oral administration; it produced mainly adenocarcinomas
of the small intestine and mammary carcinomas in female but not in
male rats and cholangiomas in female but not in male hamsters. In
addition, it produced leukaemia and reticulum-cell sarcomas in mice
following its intraperitoneal injection.
5.2 Human data
No case reports or epidemiological studies were available to the
Working Group.
Subsequent evaluation: Suppl. 7 (1987) (p. 67: Group 2B)
For definition of Groups, see Preamble Evaluation.
Synonym
- 5-Nitronaphthalene ethylene
Last updated: 26 March 1998