International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 16 (1978) (p. 163)

CAS No.: 129-17-9
Chem. Abstr. Name: N-(4-{[4-(Diethylamino)phenyl][2,4-disulfophenyl]methylene}-2,5-cyclohexadien-l-ylidene)-
N-ethylethanaminium hydroxide inner salt, sodium salt

5. Summary of Data Reported and Evaluation

5.1 Animal data

Blue VRS is carcinogenic in rats following its subcutaneous or intramuscular injection; it produced sarcomas at the site of repeated injections.

5.2 Human data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 59: Group 3)

For definition of Groups, see Preamble Evaluation.


Note: Some confusion exists in the classification of literature for blue VRS: that concerning the dye patent blue V (C.I. 42051, Acid blue 3) has been classified under 'blue VRS'.

Last updated: 26 March 1998

    See Also:
       Toxicological Abbreviations
       BLUE VRS (JECFA Evaluation)