International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 16 (1978) (p. 187)

CAS No.: 2353-45-9
Chem. Abstr. Name: N-Ethyl-N-(4-[(4-{ethyl[(3-sulfophenyl)methyl]amino}phenyl)-
(4-hydroxy-2-sulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene)-3-sulfobenzenemethanaminium hydroxide inner salt, disodium salt

5. Summary of Data Reported and Evaluation

5.1 Animal data

Fast green FCF has been tested in mice and rats by oral administration and in rats by subcutaneous injection. It was carcinogenic in rats, producing sarcomas at the site of repeated subcutaneous injections.

5.2 Human data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 63: Group 3)

For definition of Groups, see Preamble Evaluation.


  • Aizen Food Green No. 3
  • Disodium salt of 4-{[4-(N-ethyl-para-sulfobenzylamino)phenyl][4-hydroxy-2-sulfonium-
  • Ethyl[4-(a-{para-[ethyl(meta-sulfobenzyl)-amino]phenyl}-4-hydroxy-3-sulfobenzylidene)-2,5-
    cyclohexadien-1-ylidene](meta-sulfobenzyl) ammonium hydroxide inner salt, disodium salt
  • FD and C Green No. 3
  • Green 1724
  • Solid Green FCF
    Last updated: 26 March 1998
        See Also:
           Toxicological Abbreviations
           Fast green FCF  (FAO Nutrition Meetings Report Series 46a)
           Fast Green FCF (WHO Food Additives Series 16)
           Fast Green FCF (WHO Food Additives Series 20)
           Fast Green FCF (WHO Food Additives Series 21)
           FAST GREEN FCF (JECFA Evaluation)