International Agency for Research on Cancer (IARC) - Summaries & Evaluations
HEXACHLOROETHANE
VOL.: 20 (1979) (p. 467)
CAS No.: 67-72-1
5. Summary of Data Reported and Evaluation
5.1 Experimental data
Hexachloroethane was tested in one experiment in mice and in one in
rats by oral administration. In mice, it produced malignant liver
tumours in males and females. In rats, no statistically significant
excess of tumours was observed; however, a few renal tumours, rarely
seen in untreated animals, were found.
5.2 Human data
No case reports or epidemiological studies were available to the
Working Group.
The production and many uses of hexachloroethane for over 50 years,
and its occurrence in water and air, indicate that human exposure
occurs.
5.3 Evaluation
There is limited evidence that hexachloroethane is carcinogenic in
experimental animals.
Subsequent evaluations: Suppl. 7 (1987) (p. 64); Vol. 73 (1999)
For definition of terms, see Preamble Evaluation.
Synonyms
- Avlothane
- Carbon hexachloride
- Distokal
- Distopan
- Distopin
- Egitol
- Falkitol
- Fasciolin
- Hexachloroethane
- 1,1,1,2,2,2-Hexachloroethane
- Hexachloroethylene
- Mottenhexe
- Perchloroethane
- Phenohep
Last updated: 30 September 1999