International Agency for Research on Cancer (IARC) - Summaries & Evaluations
TRIPHENYLENE
VOL.: 32 (1983) (p. 447)
CAS No.: 217-59-4
5. Summary of Data Reported and Evaluation
5.1 Experimental data
Triphenylene was tested for carcinogenicity in one study by skin
application to male mice. No increase in the incidence of skin
tumours was observed.
No data on the teratogenicity of this compound were available.
Triphenylene was mutagenic to Salmonella typhimurium in the
presence of an exogenous metabolic system.
There is inadequate evidence that triphenylene is active in
short-term tests.
5.2 Human data
Triphenylene is present as a major component of the total content
of polynuclear aromatic compounds in the environment. Human exposure
to triphenylene occurs primarily through the smoking of tobacco,
inhalation of polluted air and by ingestion of food and water
contaminated by combustion effluents.
5.3 Evaluation
The available data are inadequate to permit an evaluation of the
carcinogenicity of triphenylene to experimental animals.
For definition of the italicized terms, see Preamble Evaluation.
Subsequent evaluation: Suppl. 7 (1987) (p. 73: Group 3)
Synonyms
- Benzo(1)phenanthrene
- 9,10-Benzophenanthrene
- 9,10-Benzphenanthrene
- 1,2,3,4-Dibenznaphthalene
- Isochrysene
Last updated: 17 April 1998