International Agency for Research on Cancer (IARC) - Summaries & Evaluations
VOL.: 33 (1984) (p. 201)
CAS No.: 892-21-7
Chem. Abstr. Name: Fluoranthene, 3-nitro-
5. Summary of Data Reported and Evaluation
5.1 Experimental data
In one limited experiment in which 3-nitrofluoranthene was tested in
male rats by subcutaneous injection, sarcomas were observed at the
3-Nitrofluoranthene was mutagenic to Salmonella typhimurium in the
presence and absence of an exogenous metabolic system. It induced
morphological transformation in Syrian hamster embryo cells.
5.2 Human data
Environmental exposure to 3-nitrofluoranthene occurs, as it is a
constituent of particulate matter in diesel-engine exhaust and in
urban air. It is not produced commercially.
No case report or epidemiological study was available to the Working
The available data are inadequate to permit an evaluation of the
carcinogenicity of 3-nitrofluoranthene to experimental animals.
No data on humans were available.
No evaluation of the carcinogenicity of 3-nitrofluoranthene to humans
could be made.
For definition of the italicized terms, see Preamble Evaluation.
Subsequent evaluation: Suppl. 7 (1987) (p. 67: Group 3)
Last updated: 20 April 1998