International Agency for Research on Cancer (IARC) - Summaries & Evaluations

For definition of Groups, see Preamble Evaluation.

VOL.: 46 (1989) (p. 189)

CAS No.: 105735-71-5
Chem. Abstr. Name: Fluoranthene, 3,7-dinitro-

5.1 Exposure data

3,7-Dinitrofluoranthene has been detected in the particulate fraction of the exhaust of a diesel engine.

5.2 Experimental data

3,7-Dinitrofluoranthene was tested for carcinogenicity in one experiment in rats by subcutaneous injection, producing sarcomas at the injection site.

5.3 Human data

No data were available to the Working Group.

5.4 Other relevant data

3,7-Dinitrofluoranthene induced DNA damage and mutation in bacteria.

5.5 Evaluation

There is limited evidence for the carcinogenicity in experimental animals of 3,7-dinitrofluoranthene.

No data were available from studies in humans on the carcinogenicity of 3,7-dinitrofluoranthene.

Overall evaluation

3,7-Dinitrofluoranthene is not classifiable as to its carcinogenicity to humans (Group 3).

For definition of the italicized terms, see Preamble Evaluation.

Last updated 01/21/98

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       Toxicological Abbreviations