International Agency for Research on Cancer (IARC) - Summaries & Evaluations

(Group 3)

For definition of Groups, see Preamble Evaluation.

VOL.: 46 (1989) (p. 313)

CAS No.: 20589-63-3
Chem. Abstr. Name: Perylene, 3-nitro-

5. Summary of Data Reported and Evaluation

5.1 Exposure data

No data were available to the Working Group.

5.2 Experimental carcinogenicity data

3-Nitroperylene was tested for carcinogenicity in an initiation-promotion experiment on mouse skin and was active as an initiator.

5.3 Human carcinogenicity data

No data were available to the Working Group.

5.4 Other relevant data

3-Nitroperylene was mutagenic to bacteria in the presence of an exogenous metabolic system.

5.5 Evaluation

There is inadequate evidence for the carcinogenicity in experimental animals of 3-nitroperylene.

No data were available from studies in humans on the carcinogenicity of 3-nitroperylene in humans.

Overall evaluation

3-Nitroperylene is not classifiable as to its carcinogenicity to humans (Group 3).

For definition of the italicized terms, see Preamble Evaluation.

Last updated 01/20/1998

    See Also:
       Toxicological Abbreviations