International Agency for Research on Cancer (IARC) - Summaries & Evaluations
DISPERSE YELLOW 3
(Group 3)
For definition of Groups, see Preamble Evaluation.
VOL.: 48 (1990) (p. 149)
CAS No.: 2832-40-8
Chem. Abstr. Name: Acetamide, N-{4-[(2-Hydroxy-5-methylphenyl)azo]phenyl}-
5. Summary of Data Reported and Evaluation
5.1 Exposure data
Disperse Yellow 3 is a monoazo pigment dye which has been produced
in significant quantities since the 1940s to colour fabrics and
plastics. There is potentially widespread exposure to Disperse
Yellow 3 because of its use in clothing, hosiery and carpets.
No data on occupational exposure levels were available.
5.2 Experimental carcinogenicity data
Disperse Yellow 3 was tested for carcinogenicity by oral administration
in one strain of mice and in one strain of rats. In female mice,
it produced increases in the incidences of hepatocellular tumours
and malignant lymphomas; in male mice, the incidence of alveolar/bronchiolar
adenomas was increased. In rats, it produced an increase in the
incidence of hepatocellular adenomas in males.
5.3 Human carcinogenicity data
No data were available to the Working Group.
5.4 Other relevant data
In a single study, Disperse Yellow 3 induced sister chromatid
exchange but not chromosomal aberrations in Chinese hamster cells
in culture. It was mutagenic to mouse cells in culture. Disperse
Yellow 3 was mutagenic to bacteria in the presence and absence
of an exogenous metabolic system.
5.5 Evaluation
There is limited evidence for the carcinogenicity of Disperse
Yellow 3 in experimental animals.
No data were available from studies in humans on the carcinogenicity
of Disperse Yellow 3.
Overall evaluation
Disperse Yellow 3 is not classifiable as to its carcinogenicity
to humans (Group 3).
For definition of the italicized terms, see Preamble Evaluation.
Previous evaluations: Vol. 8 (1975) (p. 97); Suppl. 7 (1987)
(p. 60)
Synonyms
- 4-Acetamido-2'-hydroxy-5'-methylazobenzene
- Acetamine Yellow CG
- Acetate Fast Yellow G
- Acetoquinone Light Yellow 4JLZ
- Altco Sperse Fast Yellow GFN new
- Amacel Yellow G
- Atrisil Yellow 2GN
- Atrisil Yellow G
- Atrisil Direct Yellow G
- Calcosyn Yellow GCN
- Celliton Discharge Yellow GL
- Celliton Fast Yellow G
- Celliton Fast Yellow GA
- Celliton Fast Yellow GA-CF
- Celliton Yellow G
- Celutate Yellow GH
- CI Disperse Yellow 3
- CI Solvent Yellow 77
- CI Solvent Yellow 92
- CI Solvent Yellow 99
- Cibacet Yellow 2GC
- Cibacete Yellow GBA
- Cilla Fast Yellow G
- Diacelliton Fast Yellow G
- Disperse Yellow G
- Disperse Yellow Z
- Dispersol Fast Yellow G
- Dispersol Printing Yellow G
- Dispersol Yellow A-G
- Dispersyl Fast Yellow J
- Durgacet Yellow G
- Durosperse Yellow G
- Eastone Yellow GN
- Esteroquinone Light Yellow 4JL
- Fenacet Fast Yellow G
- Hispacet Fast Yellow G
- Hisperse Yellow G
- 4'-(6-Hydroxy-meta-tolylazo)acetanilide
- 4'-[(2-Hydroxy-5-methylphenyl)azo]acetanilide
- 4'-[(6-Hydroxy-meta-tolyl)azo]acetanilide
- Interchem Acetate Yellow G
- Interchem Hisperse Yellow GH
- Intrasperse Yellow GBA
- Intrasperse Yellow GBA extra
- Kayalon Fast Yellow G
- Kayaset Yellow G
- KCA acetate Fast Yellow G
- Lurafix Yellow 142
- Microsetile Yellow GR
- Miketon Fast Yellow G
- N-[4-[(2-Hydroxy-5-methyphenyl)azo]phenyl]acetamide
- Nacelan Fast Yellow CG
- Navicet Yellow G
- Navilene Yellow G
- Novalon Yellow 2GN
- Nyloquinone Yellow 4J
- Ostacet Yellow P2G
- Palacet Yellow GN
- Palanil Yellow G
- Pamacel Yellow G-3
- Perliton Yellow G
- Reliton Yellow C
- Resiren Yellow TG
- Safaritone Yellow G
- Serinyl Hosiery Yellow GD
- Seriplas Yellow GD
- Serisol Fast Yellow GD
- Setacyl Yellow 2GN
- Setacyl Yellow G
- Setacyl Yellow P 2GL
- Silotras Yellow TSG
- Sumiplast Yellow FC
- Supracet Fast Yellow G
- Synten Yellow 2G
- Terasil Yellow 2GC
- Terasil Yellow GBA extra
- Tertranese Yellow N-2GL
- Transetile Yellow P-GR
- Tuladisperse Fast Yellow 2G
- Vonteryl Yellow G
- Vonteryl Yellow R
- Yellow Reliton G
- Yellow Z
Last updated 01/20/98