ICSC 0166 - HYDROQUINONE

HYDROQUINONE	ICSC: 0166 (October 2001)
1,4-Dihydroxybenzene Hydroquinol Quinol

CAS #: 123-31-9

UN #: 2662

EC Number: 204-617-8

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible. Finely dispersed particles form explosive mixtures in air.	NO open flames. Closed system, dust explosion-proof electrical equipment and lighting. Prevent deposition of dust.	Use water spray, powder, foam, carbon dioxide.

PREVENT DISPERSION OF DUST! AVOID ALL CONTACT!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Cough. Laboured breathing.	Use local exhaust or breathing protection.	Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
Skin	Redness.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse and then wash skin with water and soap.
Eyes	Redness. Pain. Blurred vision.	Wear safety goggles.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	Dizziness. Headache. Nausea. Shortness of breath. Convulsions. Vomiting. Ringing in the ears.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention .

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. Carefully collect remainder. Then store and dispose of according to local regulations.	According to UN GHS Criteria Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: III
STORAGE
Separated from strong bases and food and feedstuffs.
PACKAGING
Do not transport with food and feedstuffs.

HYDROQUINONE

ICSC: 0166

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS CRYSTALS. Physical dangers Dust explosion possible if in powder or granular form, mixed with air. Chemical dangers Reacts violently with sodium hydroxide.	Formula: C₆H₆O₂ / C₆H₄(OH)₂ Molecular mass: 110.1 Boiling point: 287°C Melting point: 172°C Relative density (water = 1): 1.3 Solubility in water, g/100ml at 15°C: 5.9 Vapour pressure, Pa at 20°C: 0.12 Relative vapour density (air = 1): 3.8 Relative density of the vapour/air-mixture at 20°C (air = 1): 1 Flash point: 165°C Auto-ignition temperature: 515°C Octanol/water partition coefficient as log Pow: 0.59

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS CRYSTALS.

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air.

Chemical dangers
Reacts violently with sodium hydroxide.

Formula: C₆H₆O₂ / C₆H₄(OH)₂
Molecular mass: 110.1
Boiling point: 287°C
Melting point: 172°C
Relative density (water = 1): 1.3
Solubility in water, g/100ml at 15°C: 5.9
Vapour pressure, Pa at 20°C: 0.12
Relative vapour density (air = 1): 3.8
Relative density of the vapour/air-mixture at 20°C (air = 1): 1
Flash point: 165°C
Auto-ignition temperature: 515°C
Octanol/water partition coefficient as log Pow: 0.59

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation, through the skin and by ingestion. Effects of short-term exposure The substance is severely irritating to the eyes. The substance is irritating to the skin and respiratory tract.	Inhalation risk A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C. Effects of long-term or repeated exposure Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the eyes and skin. This may result in discolouration of the conjunctiva and cornea and skin depigmentation. This substance is possibly carcinogenic to humans.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

Effects of short-term exposure
The substance is severely irritating to the eyes. The substance is irritating to the skin and respiratory tract.

Inhalation risk
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C.

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the eyes and skin. This may result in discolouration of the conjunctiva and cornea and skin depigmentation. This substance is possibly carcinogenic to humans.

OCCUPATIONAL EXPOSURE LIMITS
TLV: 1 mg/m³, as TWA; (SEN); A3 (confirmed animal carcinogen with unknown relevance to humans). MAK: skin absorption (H); sensitization of skin (SH); carcinogen category: 2; germ cell mutagen group: 3A

ENVIRONMENT
The substance is very toxic to aquatic organisms.

NOTES
Depending on the degree of exposure, periodic medical examination is suggested. There is no odour warning even when toxic concentrations are present.

ADDITIONAL INFORMATION

EC Classification
Symbol: Xn, N; R: 22-40-41-43-50-68; S: (2)-26-36/37/39-61

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    See Also:
       Toxicological Abbreviations
       Hydroquinone (EHC 157, 1994)
       Hydroquinone (HSG 101, 1996)
       Hydroquinone (IARC Summary & Evaluation, Volume 71, 1999)