ICSC 0241 - CROTONALDEHYDE

CROTONALDEHYDE	ICSC: 0241 (May 2018)
2-Butenal beta-Methylacrolein Methyl propenal Propylene aldehyde

CAS #: 4170-30-3

UN #: 1143

EC Number: 224-030-0

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Highly flammable. Many reactions may cause fire or explosion. Vapour/air mixtures are explosive.	NO open flames, NO sparks and NO smoking. NO contact with oxidizing agents or incompatible substances. See Chemical Dangers. Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling.	Use water spray, powder, alcohol-resistant foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water. Combat fire from a sheltered position.

PREVENT GENERATION OF MISTS! STRICT HYGIENE! IN ALL CASES CONSULT A DOCTOR!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Sore throat. Burning sensation behind the breastbone. Cough. Shortness of breath. Symptoms may be delayed. See Notes.	Use ventilation, local exhaust or breathing protection.	Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer immediately for medical attention.
Skin	Redness. Burning sensation. Pain.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer immediately for medical attention .
Eyes	Redness. Pain. Burns. Watering of the eyes.	Wear face shield or eye protection in combination with breathing protection.	Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer immediately for medical attention.
Ingestion	Burning sensation. Nausea. Abdominal pain. Vomiting. Diarrhoea.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Give one or two glasses of water to drink. Refer immediately for medical attention.

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Evacuate danger area! Consult an expert! Personal protection: chemical protection suit including self-contained breathing apparatus. Remove all ignition sources. Ventilation. Do NOT absorb in saw-dust or other combustible absorbents. Do NOT wash away into sewer. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable non-plastic containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Wash away remainder with plenty of water. Then store and dispose of according to local regulations.	According to UN GHS Criteria DANGER Highly flammable liquid and vapour Fatal in contact with skin or if inhaled Toxic if swallowed Causes skin and eye irritation May cause respiratory irritation May cause damage to liver through prolonged or repeated exposure Toxic to aquatic life Transportation UN Classification UN Hazard Class: 6.1; UN Subsidiary Risks: 3; UN Pack Group: I
STORAGE
Fireproof. Separated from food and feedstuffs and incompatible materials. See Chemical Dangers. Cool. Keep in the dark. Well closed. Store only if stabilized. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.
PACKAGING
Airtight. Unbreakable packaging. Put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs. Marine pollutant.

CROTONALDEHYDE

ICSC: 0241

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS LIQUID WITH PUNGENT ODOUR. TURNS PALE YELLOW ON EXPOSURE TO LIGHT AND AIR. Physical dangers The vapour is heavier than air and may travel along the ground; distant ignition possible. Chemical dangers The substance can presumably form explosive peroxides. The substance may polymerize. This generates fire or explosion hazard. The substance is a strong reducing agent. It reacts violently with oxidants and many other substances. This generates fire and explosion hazard. Attacks plastics and many other substances.	Formula: C₄H₆O / CH₃CH=CHCHO Molecular mass: 70.1 Boiling point: 104°C Melting point: -76.5°C (trans), -69°C (cis) Relative density (water = 1): 0.85 Solubility in water, g/100ml at 20°C: 15-18 (freely soluble) Vapour pressure, kPa at 20°C: 4.0 Relative vapour density (air = 1): 2.41 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.06 Flash point: 13°C c.c. Auto-ignition temperature: 232°C Explosive limits, vol% in air: 2.1-15.5 Octanol/water partition coefficient as log Pow: 0.63 (calculated)

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID WITH PUNGENT ODOUR. TURNS PALE YELLOW ON EXPOSURE TO LIGHT AND AIR.

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible.

Chemical dangers
The substance can presumably form explosive peroxides. The substance may polymerize. This generates fire or explosion hazard. The substance is a strong reducing agent. It reacts violently with oxidants and many other substances. This generates fire and explosion hazard. Attacks plastics and many other substances.

Formula: C₄H₆O / CH₃CH=CHCHO
Molecular mass: 70.1
Boiling point: 104°C
Melting point: -76.5°C (trans), -69°C (cis)
Relative density (water = 1): 0.85
Solubility in water, g/100ml at 20°C: 15-18 (freely soluble)
Vapour pressure, kPa at 20°C: 4.0
Relative vapour density (air = 1): 2.41
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.06
Flash point: 13°C c.c.
Auto-ignition temperature: 232°C
Explosive limits, vol% in air: 2.1-15.5
Octanol/water partition coefficient as log Pow: 0.63 (calculated)

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. Effects of short-term exposure Lachrymation. The vapour is severely irritating to the skin, eyes and respiratory tract. Inhalation of high concentrations may cause lung oedema. See Notes. Exposure far above the OEL could cause death. Medical observation is indicated.	Inhalation risk A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. Effects of long-term or repeated exposure The substance may have effects on the liver and respiratory tract. Tumours have been detected in experimental animals but may not be relevant to humans.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion.

Effects of short-term exposure
Lachrymation. The vapour is severely irritating to the skin, eyes and respiratory tract. Inhalation of high concentrations may cause lung oedema. See Notes. Exposure far above the OEL could cause death. Medical observation is indicated.

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.

Effects of long-term or repeated exposure
The substance may have effects on the liver and respiratory tract. Tumours have been detected in experimental animals but may not be relevant to humans.

OCCUPATIONAL EXPOSURE LIMITS
TLV: 0.3 ppm as STEL; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans). MAK: skin absorption (H); carcinogen category: 3; germ cell mutagen group: 3A

ENVIRONMENT
The substance is toxic to aquatic organisms. It is strongly advised not to let the chemical enter into the environment.

NOTES
The occupational exposure limit value should not be exceeded during any part of the working exposure. Rinse contaminated clothing with plenty of water because of fire hazard. Check for peroxides prior to distillation; eliminate if found. Crotonaldehyde is stabilized with water. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. The CAS number is for mixed isomers (CAS 4170-30-3, EC number 224-030-0). Other CAS numbers: 123-73-9 (trans isomer, EC number 204-647-1), 15798-64-8 (cis isomer).

NOTES

The occupational exposure limit value should not be exceeded during any part of the working exposure.
Rinse contaminated clothing with plenty of water because of fire hazard.
Check for peroxides prior to distillation; eliminate if found.
Crotonaldehyde is stabilized with water.
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential.
The CAS number is for mixed isomers (CAS 4170-30-3, EC number 224-030-0). Other CAS numbers: 123-73-9 (trans isomer, EC number 204-647-1), 15798-64-8 (cis isomer).

ADDITIONAL INFORMATION

EC Classification

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    See Also:
       Toxicological Abbreviations
       Crotonaldehyde (IARC Summary & Evaluation, Volume 63, 1995)