ICSC 0520 - NICOTINE SULFATE

NICOTINE SULFATE	ICSC: 0520 (September 1997)
(-)-1-Methyl-2-(3-pyridyl)-pyrrolidine sulfate (S)-3-(1-Methyl-2-pyrrolidinyl)-pyridine sulfate 3-(1-Methyl-2-pyrrolidinyl)-pyridine sulfate

CAS #: 65-30-5

UN #: 1658

EC Number: 200-606-7

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Use water spray, powder, alcohol-resistant foam, carbon dioxide.

PREVENT DISPERSION OF DUST! AVOID EXPOSURE OF (PREGNANT) WOMEN! IN ALL CASES CONSULT A DOCTOR!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Nausea. Vomiting. Abdominal pain. Headache. Convulsions.	Use ventilation (not if powder), local exhaust or breathing protection.	Fresh air, rest. Refer for medical attention.
Skin	MAY BE ABSORBED! Redness. Pain. See Inhalation.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
Eyes	Pain. Redness.	Wear face shield or eye protection in combination with breathing protection if powder.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	See Inhalation.	Do not eat, drink, or smoke during work.	Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention .

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT wash away into sewer. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Then store and dispose of according to local regulations.	According to UN GHS Criteria Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: II
STORAGE
Provision to contain effluent from fire extinguishing. Separated from strong oxidants and food and feedstuffs.
PACKAGING
Do not transport with food and feedstuffs.

NICOTINE SULFATE

ICSC: 0520

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS CRYSTALS. Physical dangers Chemical dangers Decomposes on heating. This produces toxic fumes of sulfur oxides and nitrogen oxides. Reacts violently with strong oxidants.	Formula: C₂₀H₂₆N₄.O₄S Molecular mass: 418.6 Relative density (water = 1): 1.15 Solubility in water: good Relative vapour density (air = 1): 14.5 Flash point: see Notes Auto-ignition temperature: 244°C

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS CRYSTALS.

Physical dangers

Chemical dangers
Decomposes on heating. This produces toxic fumes of sulfur oxides and nitrogen oxides. Reacts violently with strong oxidants.

Formula: C₂₀H₂₆N₄.O₄S
Molecular mass: 418.6
Relative density (water = 1): 1.15
Solubility in water: good
Relative vapour density (air = 1): 14.5
Flash point: see Notes
Auto-ignition temperature: 244°C

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. Effects of short-term exposure The substance is irritating to the eyes and skin. The substance may cause effects on the central nervous system. This may result in convulsions and respiratory failure. Exposure at high concentrations could cause death. The effects may be delayed. Medical observation is indicated.	Inhalation risk Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered. Effects of long-term or repeated exposure Animal tests show that this substance possibly causes toxic effects upon human reproduction.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.

Effects of short-term exposure
The substance is irritating to the eyes and skin. The substance may cause effects on the central nervous system. This may result in convulsions and respiratory failure. Exposure at high concentrations could cause death. The effects may be delayed. Medical observation is indicated.

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered.

Effects of long-term or repeated exposure
Animal tests show that this substance possibly causes toxic effects upon human reproduction.

OCCUPATIONAL EXPOSURE LIMITS

ENVIRONMENT
The substance is toxic to aquatic organisms.

NOTES
The substance is combustible but no flash point is available in literature.

ADDITIONAL INFORMATION

EC Classification
Symbol: T+, N; R: 26/27/28-51/53; S: (1/2)-13-28-45-61; Note: A

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    See Also:
       Toxicological Abbreviations