ICSC 0686 - TRIMETHYL PHOSPHATE

TRIMETHYL PHOSPHATE	ICSC: 0686 (October 2004)
Phosphoric acid trimethyl ester Trimethyl orthophosphate

CAS #: 512-56-1

EC Number: 208-144-8

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Use water spray, alcohol-resistant foam, dry powder, carbon dioxide.

AVOID ALL CONTACT!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Cough. Sore throat.	Use ventilation, local exhaust or breathing protection.	Fresh air, rest. Refer for medical attention.
Skin	Redness.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse skin with plenty of water or shower.
Eyes	Redness.	Wear safety goggles.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	Shortness of breath. Weakness. Hyperexcitability. Tremor.	Do not eat, drink, or smoke during work.	Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention .

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus. Ventilation. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.	According to UN GHS Criteria Transportation UN Classification
STORAGE
Separated from strong oxidants and strong bases.
PACKAGING

TRIMETHYL PHOSPHATE

ICSC: 0686

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS LIQUID. Physical dangers Chemical dangers Decomposes on burning. This produces toxic fumes including phosphorus oxides. Reacts with strong bases and strong oxidants. May explode on heating during large scale atmospheric pressure distillation.	Formula: C₃H₉O₄P / (CH₃O)₃PO Molecular mass: 140.1 Boiling point: 197.2°C Melting point: -46°C Relative density (water = 1): 1.2 Solubility in water, g/100ml at 25°C: 50 (good) Vapour pressure, kPa at 20°C: 0.11 Flash point: 107°C Octanol/water partition coefficient as log Pow: -0.52,-0.78

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID.

Physical dangers

Chemical dangers
Decomposes on burning. This produces toxic fumes including phosphorus oxides. Reacts with strong bases and strong oxidants. May explode on heating during large scale atmospheric pressure distillation.

Formula: C₃H₉O₄P / (CH₃O)₃PO
Molecular mass: 140.1
Boiling point: 197.2°C
Melting point: -46°C
Relative density (water = 1): 1.2
Solubility in water, g/100ml at 25°C: 50 (good)
Vapour pressure, kPa at 20°C: 0.11
Flash point: 107°C
Octanol/water partition coefficient as log Pow: -0.52,-0.78

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. Effects of short-term exposure The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the nervous system.	Inhalation risk No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C. Effects of long-term or repeated exposure The substance may have effects on the nervous system. This may result in flaccid paralysis. May cause heritable genetic damage to human germ cells.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion.

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the nervous system.

Inhalation risk
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C.

Effects of long-term or repeated exposure
The substance may have effects on the nervous system. This may result in flaccid paralysis. May cause heritable genetic damage to human germ cells.

OCCUPATIONAL EXPOSURE LIMITS
MAK: sensitization of skin (SH); carcinogen category: 3; germ cell mutagen group: 2

ENVIRONMENT

NOTES

ADDITIONAL INFORMATION

EC Classification

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    See Also:
       Toxicological Abbreviations