ICSC 0845 - CHLOROACETYL CHLORIDE

CHLOROACETYL CHLORIDE	ICSC: 0845 (March 1998)
Chloroacetic acid chloride Monochloroacetyl chloride

CAS #: 79-04-9

UN #: 1752

EC Number: 201-171-6

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.		In case of fire in the surroundings, use appropriate extinguishing media. In case of fire: keep drums, etc., cool by spraying with water. NO direct contact with water.

AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Cough. Laboured breathing. Burning sensation. Blue lips, fingernails and skin. Shortness of breath. Sore throat. Symptoms may be delayed. See Notes.	Use ventilation, local exhaust or breathing protection.	Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
Skin	MAY BE ABSORBED! Redness. Pain. Serious skin burns. Blisters.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .
Eyes	Pain. Redness. Blurred vision. Severe deep burns.	Wear face shield or eye protection in combination with breathing protection.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	Burning sensation. Abdominal pain. Diarrhoea. Shock or collapse.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Do NOT induce vomiting. Give nothing to drink. Refer for medical attention . See Notes.

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Cover the spilled material with dry sand. Collect leaking and spilled liquid in sealable containers as far as possible. Then store and dispose of according to local regulations. NEVER direct water jet on liquid. Personal protection: complete protective clothing including self-contained breathing apparatus.	According to UN GHS Criteria Transportation UN Classification UN Hazard Class: 6.1; UN Subsidiary Risks: 8; UN Pack Group: I
STORAGE
Separated from food and feedstuffs. See Chemical Dangers. Dry. Keep in a well-ventilated room.
PACKAGING
Unbreakable packaging. Put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs.

CHLOROACETYL CHLORIDE

ICSC: 0845

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS-TO-YELLOW LIQUID WITH PUNGENT ODOUR. Physical dangers The vapour is heavier than air. Chemical dangers Decomposes on heating. This produces toxic and corrosive fumes including phosgene and hydrogen chloride. Reacts violently with water, alcohols, powdered metals and many organics. This generates toxic, fire and explosion hazard. Contact with air generates corrosive gas.	Formula: C₂H₂Cl₂O / ClCH₂COCl Molecular mass: 112.9 Boiling point: 106°C Melting point: -21.8°C Relative density (water = 1): 1.4 Solubility in water: reaction Vapour pressure, kPa at 20°C: 2.5 Relative vapour density (air = 1): 3.9 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.07

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS-TO-YELLOW LIQUID WITH PUNGENT ODOUR.

Physical dangers
The vapour is heavier than air.

Chemical dangers
Decomposes on heating. This produces toxic and corrosive fumes including phosgene and hydrogen chloride. Reacts violently with water, alcohols, powdered metals and many organics. This generates toxic, fire and explosion hazard. Contact with air generates corrosive gas.

Formula: C₂H₂Cl₂O / ClCH₂COCl
Molecular mass: 112.9
Boiling point: 106°C
Melting point: -21.8°C
Relative density (water = 1): 1.4
Solubility in water: reaction
Vapour pressure, kPa at 20°C: 2.5
Relative vapour density (air = 1): 3.9
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.07

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation of its aerosol or vapour, through the skin and by ingestion. Effects of short-term exposure Lachrymation. The substance is corrosive to the skin and respiratory tract. The substance is irritating to the eyes. Corrosive on ingestion. Inhalation of the vapour or aerosol may cause lung oedema. See Notes. The substance may cause effects on the cardiovascular system. Exposure far above the OEL could cause death. The effects may be delayed. Medical observation is indicated.	Inhalation risk A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. Effects of long-term or repeated exposure Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged inhalation may cause effects on the lungs.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol or vapour, through the skin and by ingestion.

Effects of short-term exposure
Lachrymation. The substance is corrosive to the skin and respiratory tract. The substance is irritating to the eyes. Corrosive on ingestion. Inhalation of the vapour or aerosol may cause lung oedema. See Notes. The substance may cause effects on the cardiovascular system. Exposure far above the OEL could cause death. The effects may be delayed. Medical observation is indicated.

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged inhalation may cause effects on the lungs.

OCCUPATIONAL EXPOSURE LIMITS
TLV: 0.05 ppm as TWA; 0.15 ppm as STEL; (skin). MAK skin absorption (H)

ENVIRONMENT

NOTES
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Do NOT take working clothes home.

ADDITIONAL INFORMATION

EC Classification
Symbol: T, C, N; R: 14-23/24/25-35-48/23-50; S: (1/2)-7/8-9-26-36/37/39-45-61

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    See Also:
       Toxicological Abbreviations