ICSC 1703 - NICOTINAMIDE

NICOTINAMIDE	ICSC: 1703 (April 2008)
Pyridine-3-carboxylamide 3-Pyridinecarboxamide Niacinamide

CAS #: 98-92-0

EC Number: 202-713-4

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Finely dispersed particles form explosive mixtures in air.	Prevent deposition of dust. Closed system, dust explosion-proof electrical equipment and lighting.	Use water spray, foam, powder, carbon dioxide.

PREVENT DISPERSION OF DUST!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Cough.	Avoid inhalation of dust.	Fresh air, rest.
Skin		Protective gloves.	Rinse skin with plenty of water or shower.
Eyes	Redness. Pain.	Wear safety goggles.	Rinse with plenty of water (remove contact lenses if easily possible).
Ingestion		Do not eat, drink, or smoke during work.	Rinse mouth. Give one or two glasses of water to drink.

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water.	According to UN GHS Criteria WARNING Causes eye irritation Transportation UN Classification
STORAGE
Separated from oxidants.
PACKAGING

NICOTINAMIDE

ICSC: 1703

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance WHITE CRYSTALLINE POWDER. Physical dangers Dust explosion possible if in powder or granular form, mixed with air. Chemical dangers On combustion, forms toxic gases including nitrogen oxides. Reacts with oxidants.	Formula: C₆H₆N₂O Molecular mass: 122.1 Sublimation Melting point: 127-131°C Density: 1.4 g/cm³ Solubility in water, g/100ml at 20°C: 100 (very good) Vapour pressure, kPa at 35°C: 3.1 Relative vapour density (air = 1): 4.2 Flash point: 182°C Auto-ignition temperature: 480°C Octanol/water partition coefficient as log Pow: -0.38

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
WHITE CRYSTALLINE POWDER.

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air.

Chemical dangers
On combustion, forms toxic gases including nitrogen oxides. Reacts with oxidants.

Formula: C₆H₆N₂O
Molecular mass: 122.1
Sublimation
Melting point: 127-131°C
Density: 1.4 g/cm³
Solubility in water, g/100ml at 20°C: 100 (very good)
Vapour pressure, kPa at 35°C: 3.1
Relative vapour density (air = 1): 4.2
Flash point: 182°C
Auto-ignition temperature: 480°C
Octanol/water partition coefficient as log Pow: -0.38

EXPOSURE & HEALTH EFFECTS
Routes of exposure Effects of short-term exposure The substance is irritating to the eyes.	Inhalation risk A nuisance-causing concentration of airborne particles can be reached quickly when dispersed, especially if powdered. Effects of long-term or repeated exposure

EXPOSURE & HEALTH EFFECTS

Routes of exposure

Effects of short-term exposure
The substance is irritating to the eyes.

Inhalation risk
A nuisance-causing concentration of airborne particles can be reached quickly when dispersed, especially if powdered.

Effects of long-term or repeated exposure

OCCUPATIONAL EXPOSURE LIMITS

ENVIRONMENT

NOTES

ADDITIONAL INFORMATION

EC Classification

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    See Also:
       Toxicological Abbreviations