| OXYTETRACYCLINE | |
| Chemical names: | 4-(DIMETHYLAMINO)-1,4,4a,5,5a,6,11,12a-OCTAHYDRO-3,5,6,10,12,12a-HEXAHYDRO-6-METHYL- 1,11-DIOXO-2-NAPHTHACENECARBOXAMIDE | Functional class: | VETERINARY DRUG (ANTIMICROBIAL AGENT) | Latest evaluation: | 2002 | ADI: | 0-0.03 mg/kg bw (1998) | Comments: | Group ADI for tetracycline, oxytetracycline and chlortetracycline, established at the fiftieth meeting (1998) | Comments/MRLs: | MRL: Muscle (fish): 0.2 mg/kg. This MRL applies only to oxytetracycline. The MRLs recommended in cattle, pigs, sheep, poultry and giant tiger prawn (Penaeus monodon) at the fiftieth meeting (1998) were not reconsidered and were maintained. | Report: | TRS 911-JECFA 58/33 | Residues: | FNP 41/14-JECFA 58/61 | Tox monograph: | FAS 41-JECFA 50/69 (1998) | Previous status: | 2000, TRS 900-JECFA 54/29, FNP 41/13-JECFA 54/124, FAS 41-JECFA 50/69 (1998). 0-0.03 mg/kg bw (1998). THE MRLs RECOMMENDED AT THE FIFTIETH MEETING (1998) FOR CATTLE, PIGS, SHEEP, POULTRY, AND GIANT TIGER PRAWN (Penaeus monodon) WERE NOT RECONSIDERED AND WERE MAINTAINED. THE TEMPORARY MRL FOR FISH WAS EXTENDED TO 2002
1998, TRS 888-JECFA 50/50, FNP 41/11-JECFA 50/23, FAS 41-JECFA 50/69. 0-0.03. GROUP ADI AND GROUP MRLS FOR CHLORTETRACYCLINE, OXYTETRACYCLINE, AND TETRACYCLINE, EXPRESSED AS PARENT DRUG, SINGLY OR IN COMBINATION; MRLS: MUSCLE (CATTLE, PIGS, SHEEP, POULTRY, FISH (TEMPORARY), AND GIANT TIGER PRAWN (PENAEUS MONODON)): 0.2; LIVER (CATTLE, PIGS, SHEEP AND POULTRY): 0.6; KIDNEY (CATTLE, PIGS, SHEEP AND POULTRY): 1.2; EGGS (POULTRY): 0.4; MILK (CATTLE AND SHEEP): 0.1. FU. MRL/TMRL 1996, TRS 876-JECFA 47/22, FNP 41/9-JECFA 47/3, FAS 36-JECFA 45/85 (1995). 0-0.003 (1995). GROUP ADI AND GROUP MRLs FOR CHLORTETRACYCLINE, OXYTETRACYCLINE, AND TETRACYCLINE, EXPRESSED AS PARENT DRUG, SINGLY OR IN COMBINATION; MRLs: MUSCLE (CATTLE, PIGS, SHEEP AND POULTRY): 0.1; LIVER (CATTLE, PIGS, SHEEP AND POULTRY): 0.3; KIDNEY (CATTLE, PIGS, SHEEP AND POULTRY): 0.6; EGGS (POULTRY): (0.2); MILK (CATTLE AND SHEEP): 0.1. FU, MRL 1995, TRS 864-JECFA 45/38, FNP 41/8-JECFA 45/125, FAS 27-JECFA 36/117 (1990). 0-0.003. GROUP ADI FOR CHLORTETRACYCLINE, OXYTETRACYCLINE, AND TETRACYCLINE; MRL (TEMPORARY; EXPRESSED AS PARENT DRUG): EDIBLE TISSUE OF GIANT SQUID (PENAEUS MONODON): 0.1. FU. TMRL 1990, TRS 799-JECFA 36/41, FNP 41/3-JECFA 36/97, FAS 27-JECFA 36/117. 0-0.003. (MRLs (ALL SPECIES): MUSCLE: 0.1; LIVER: 0.3; KIDNEY: 0.6; FAT: 0.01; MILK: 0.1; EGGS: 0.2). FU. TMRL 1968, NMRS 45/TRS 430-JECFA 12/38, FAS 69.34/NMRS 45A-JECFA 12/76, NMRS 45/TRS 430-JECFA 12/38. 0-0.15 (TEMPORARY). ACCEPTABLE LEVELS OF RESIDUES (CALCULATED AS BASE): MILK: 0-0.1; MEAT: 0-0.25; EGGS: 0-0.3. TE. N |
| 12 Jan 04 | |
See Also:
Toxicological Abbreviations
Oxytetracycline (WHO Food Additives Series 27)