| TETRACYCLINE | |
| Chemical names: | 4-(DIMETHYLAMINO)-1,4,4a,5,5a,6,11,12a-OCTAHYDRO-3,6,10,12,12a-PENTAHYDROXY-6-METHYL-1,11-DIOXO-2-NAPHTHALENECARBOXAMIDE | Functional class: | VETERINARY DRUG (ANTIMICROBIAL AGENT) | Latest evaluation: | 1998 | ADI: | 0-0.03 mg/kg bw | Comments: | Group ADI for tetracycline, oxytetracycline and chlortetracycline, established at the fiftieth meeting (1998) | Comments/MRLs: | Group ADI and group MRLs for chlortetracycline, oxytetracycline, and tetracycline, expressed as parent drug, singly or in combination; MRLs (in mg/kg tissue, mg/l milk): Muscle (cattle, pigs, sheep and poultry): 0.2; Liver (cattle, pigs, sheep and poultry): 0.6; Kidney (cattle, pigs, sheep and poultry): 1.2; Eggs (poultry): 0.4; Milk (cattle and sheep): 0.1 At the fifty-fourth meeting (2000), in connection with the Committee's review of the MRL for oxytetracycline in fish, these group MRLs were not considered and were maintained (see TRS 900-JECFA 54/29). | Report: | TRS 888-JECFA 50/50 | Residues: | FNP 41/11-JECFA 50/23 | Tox monograph: | FAS 41-JECFA 50/69 | Previous status: | 1996, TRS 876-JECFA 47/22, FNP 41/9-JECFA 47/3, FAS 36-JECFA 45/85 (1995). 0-0.003 (1995). GROUP ADI AND GROUP MRLs FOR CHLORTETRACYCLINE, OXYTETRACYCLINE, AND TETRACYCLINE, EXPRESSED AS PARENT DRUG, SINGLY OR IN COMBINATION; MRLs: MUSCLE (CATTLE, PIGS, SHEEP AND POULTRY): 0.1; LIVER (CATTLE, PIGS, SHEEP AND POULTRY): 0.3; KIDNEY (CATTLE, PIGS, SHEEP AND POULTRY): 0.6; EGGS (POULTRY): (0.2); MILK (CATTLE AND SHEEP): 0.1. FU, MRL
1995, TRS 864-JECFA 45/32, FNP 41/8-JECFA 45/131. FAS 36-JECFA 45/85. 0-0.003. GROUP ADI FOR CHLORTETRACYLINE, OXYTETRACYCLINE, AND TETRACYCLINE; MRLs (TEMPORARY; EXPRESSED AS PARENT DRUG): MUSCLE (CATTLE, PIGS AND POULTRY): 0.1; LIVER (CATTLE, PIGS, SHEEP AND POULTRY): 0.3; KIDNEY (CATTLE, PIGS, SHEEP AND POULTRY): 0.6; EGGS (POULTRY): 0.2. FU. TMRL 1968, NMRS 45/TRS 430-JECFA 12/38, FAS 69.34/NMRS 45A-JECFA 12/69, NMRS 45/TRS 430-JECFA 12/38. 0-0.15 (TEMPORARY). (ACCEPTABLE LEVELS OF RESIDUES (CALCULATED AS BASE): MILK: 0-0.1; MEAT: 0-0.5; EGGS: 0-0.3). TE. N |
| 30 Jan 03 | |
See Also:
Toxicological Abbreviations