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Summary of Evaluations Performed by the
Joint FAO/WHO Expert Committee on Food Additives

CARMINES
INS: 120
Chemical names: HYDRATED ALUMINIUM CHELATE OF CARMINIC ACID (7-beta-D-GLUCOPYRANOSYL-3,5,6,8- TETRAHYDROXY-1-METHYL-9,10-DIOXOANTHRACENE-2-CARBOXYLIC ACID)
Synonyms: CARMINE; COCHINEAL CARMINE; C.I. NATURAL RED 4
Functional class: COLOUR
Colour class: ANTHRAQUINONE
Colour code: C.I. (1975) No.75470
Latest evaluation: 2000
ADI: 0-5 mg/kg bw (1982)
Comments: At the fifty-fifth meeting (2000), the 1982 ADI of 0-5 mg/kg bw for carmines, as ammonium carmine or the equivalent of calcium, potassium and sodium salts, was not reconsidered and was maintained.
Report: TRS 901-JECFA 55/10
Specifications: COMPENDIUM ADDENDUM 10/FNP 52 Add.10/34 (METALS LIMITS) (2002)
Tox monograph: FAS 17-JECFA 26/59 (1982)
Addendum: FAS 46-JECFA 55/9
Previous status: 2000, COMPENDIUM ADDENDUM 8/FNP 52 Add.8/39. R
1995, COMPENDIUM ADDENDUM 3/FNP 52 Add.3/29. R
1993, COMPENDIUM ADDENDUM 2/FNP 52 Add.2/21. R
1982, TRS 683-JECFA 26/22, FNP 25-JECFA 26/60 (COMPENDIUM/373), FAS 17-JECFA 26/59. 0-5 (ADI INCLUDES AMMONIUM CARMINE OR THE EQUIVALENT OF CALCIUM, POTASSIUM OR SODIUM SALTS). FU. R
1981, TRS 669-JECFA 25/19, FNP 19-JECFA 25/58, FAS 16-JECFA 25/74. 0-2.5 (TEMPORARY; ADI INCLUDES AMMONIUM CARMINE OR THE EQUIVALENT AMOUNTS OF THE CALCIUM, POTASSIUM OR SODIUM SALTS). TE. N,T
1977, TRS 617-JECFA 21/18, FAS 12-JECFA 21/74. NO ADI ALLOCATED. NO. S (COCHINEAL, CARMINE AND CARMINIC ACID)
1974, NMRS 54/TRS 557-JECFA 18/17, FAS 6/NMRS 54A-JECFA 18/78. NO ADI ALLOCATED. NO. S (COCHINEAL AND CARMINIC ACID)
1959, NMRS VOL II-IV/43. N (COCHINEAL AND CARMINIC ACID)
Allergenicity: TRS 999-JECFA 55/10; FAS 46-JECFA 55/9. The Committee concluded that cochineal extract, carmines, and possibly carminic acid in foods and beverages may provoke allergic reactions in some individuals.
 
9 Mar 03    




    See Also:
       Toxicological Abbreviations
       Carmines (WHO Food Additives Series 17)