Step A3 Does intake exceed the threshold for human intake? (µg/day)^c

Step A4 Is the flavouring agent or are its metabolites endogenous?

Step A5 Adequate margin of safety for the flavouring agent or related substance?

Comments

Conclusion for flavouring agent or congeneric groups based on current intake

Step A6. Are all of the congeneric groups in the flavouring agent or NFC determined to be of no safety concern?

Conclusion for NFC based on current intake

No
USA: 353

NR

NR

See Annex 1, reference 138

No safety concern

Yes

Bois de rose oil would not be expected to be of safety concern based on current intake