INTERNATIONAL PROGRAMME ON CHEMICAL SAFETY

    WORLD HEALTH ORGANIZATION



    SUMMARY OF TOXICOLOGICAL DATA OF CERTAIN FOOD ADDITIVES
    AND CONTAMINANTS



    WHO FOOD ADDITIVES SERIES NO. 13






    The data contained in this document were examined by the
    Joint FAO/WHO Expert Committee on Food Additives*
    Rome, 3-12 April 1978




    Food and Agriculture Organization of the United Nations
    World Health Organization



    * Twenty-second Report of the Joint FAO/WHO Expert Committee on Food
    Additives, Geneva, 1978, WHO Technical Report Series No. 631

    PONCEAU 4R

    Explanation

         Ponceau 4R was previously reviewed at the 1964, 1969, 1974 and
    1977 Joint FAO/WHO Expert Committee on Food Additives. The metabolic,
    long-term and reproduction studies requested by June 1978 have not
    been provided. The long-term toxicity in mice submitted was reviewed
    at the 1974 meeting. The correct reference, however, was omitted from
    the list of references. References should be amended to include:

         Mason, P. L., Gaunt, I. F., Butterworth, K. R. and Hardy, J.
    (1974) Long term toxicity study of Ponceau 4R in mice. Submitted by
    British Industrial Biological Association, Report No. 1/1974,
    unpublished

    See Also:
       Toxicological Abbreviations
       Ponceau 4R  (FAO Nutrition Meetings Report Series 46a)
       Ponceau 4R (WHO Food Additives Series 6)
       Ponceau 4R (WHO Food Additives Series 18)
       PONCEAU 4R (JECFA Evaluation)