ANNEX 2
ABBREVIATIONS USED IN THE MONOGRAPHS
AAF acetylaminofluorine
ADI acceptable daily intake
ALD aldrin epoxidase
AP alkaline phosphatase
BBN N-butyl-N-(4-hydroxybutyl)nitrosamine
BCF bioconcentration factor
BH biphenyl-4-hydroxylase
BHA butylated hydroxyanisole
BHT butylated hydroxytoluene
BHT-MeOH 2,6-di-tert-butyl-4-hydroxy-methylphenol
BOS buthionine sulfoximine
BPDEI benzo[a]pyrene-7,8-diol-9,10-oxide
BUN blood urea nitrogen
b.w. body weight
4-CG 4-chlorogalactose
CHO chinese hamster ovary
CNS central nervous system
DBQ 2,6-di-tert-butyl-1,4-benzoquinone
1,6-DCF 1,6-dichlorofructose
DDT dichlorodiphenyltrichloroethane
DEM diethyl maleate
DEN diethylnitrosamine
DSS dioctyl sodium sulfosuccinate
DMBA 7,12-dimethylbenz[a] anthracene
DMC dimethylcarbonate
DMDC dimethyldicarbonate
DMH 1,2- dimethyl hydrazine
EH epoxide hydrolase
EOD 7-ethoxycoumarin deethylase
FAO Food and Agriculture Organization of the United Nations
FEMA Flavor and Extract Manufacturers' Association
GLDH glutamate dehydrogenase
GOT glutamate-oxalate-transaminase
GPT glutamate-pyruvate-transaminase
GSH glutathione
GST glutathione transferase
Hb heamoglobin
i.m. intramuscular
i.p. intraperitoneal
IARC International Agency for Research on Cancer
IPCS International Programme on Chemical Safety
i.v. intravenous
JECFA Joint FAO/WHO Expert Committee on Food Additives
LD50 lethal dose, median
LDH lactate dehydrogenase
3-MC 3-methyl cholanthrene
MC methyl carbamate
MCH mean cell haemoglobin
MCV mean cell volume
MEL minimum effect level
MFO mixed function oxidase
MMU N-methoxymethyl-o-methyl urethane
MNNG methyl-n-nitrosoguanidine
MP methylprednisolone
MRL maximum residue limit
MTD maximum tolerated dose
NDEA N-nitrosodiethylamine
NK natural killer
NOAEL no-observed-adverse-effect level
NOEL no-observed-effect level
ODC ornithine decarboxylase
PAPS 3'-phosphoadenosine-5'phosphosulfonate
PB phenobarbital
PBL peripheral blood lymphocyte
PEPCK phosphoenolpyruvate carboxykinase
p.o. per os (by mouth)
ppb parts per billion
ppm parts per million
PTWI provisional tolerable weekly intake
RA retinyl acetate
RBC red blood cell
sc subcutaneous(ly)
SCE sister chromatid exchange
SPL splenic leukocytes
T3 3,5,3'-triiodothyronine
rT3 3,3',5'-triiodothyronine
T4 thyroxine
TGS trichlorogalactosucrose
TPA 12-0-tetradecanoyl phorbol-13-acetate
TSH thyrotropin
UDS unscheduled DNA synthesis
WHO World Health Organization