ANNEX 2
ABBREVIATIONS USED IN THE MONOGRAPHS
ADI acceptable daily intake
ALAT alanine aminotransferase
ASAT aspartate aminotransferase
BAP benzo [a]pyrene
BUN blood urea nitrogen
bw body weight
CFM cassava foliage meal
ChE cholinesterase
CHL Chinese hamster lung
CNS central nervous system
CRM cassava root meal
d day
DBP dibenzpyrene
DEM diethyl maleate
Diff differential white blood cells
DMBA 7,12 dimethyl-1,2-benzanthracene
DMH dimethylhydrazine
ECG electrocardiogram
ED50 effective dose, median
EC50 effective concentration, median
EDTA ethylene diamine tetraacetic acid
EEC European Economic Community
EHEN N-ethyl-N-hydroxyethylnitrosamine
ENG electronystagmogrpahy
EPA Environmental Protection Agency (U.S.)
Er erythrocytes
F female
F1 filial generation, first
F2 filial generation, second
FAO Food and Agriculture Organization of the United
Nations
h hour
Hb haemoglobin
HDL high density lipoprotein
HPLC high performance liquid chromatography
Ht haematocrit
IARC International Agency for Research on Cancer
ID50 inhibitory dose, 50%
i.m. intramuscular
i.p. intraperitoneal
IPCS International Programme on Chemical Safety
i.v. intravenous
JECFA Joint FAO/WHO Expert Committee on Food Additives
KLH keyhole limpet haemocyanin
LD50 lethal dose, median
LDH lactate dehydrogenase
LDLO lethal dose, lowest
Leu leucocytes
LPO lipid peroxidation
M male
3-MCA 3-methylcholanthrene
min minute
MCHC mean corpuscular haemoglobin concentration
MCV mean cell volume
MMII mean maximum irritation index
MTD maximum tolerated dose
NBR NCI-Black-Reiter rats
NCI National Cancer Institute (USA)
NMU nitrosomethylurea
NOEL no-observed-effect level
NTD neural tube defects
NTP National Toxicology Program (U.S.)
OCT ornithylcarbamyl transferase
OECD Organization for Economic Cooperation and Development
8-OH-dG 8-hydroxydeoxyguanosine
OII ocular irritation index
OKN opticokinetic nystagmus
p.c. percutaneous
PBI protein-bound iodine
p.o. per os (by month)
PCB polychlorinated biphenyl
PCT proximal covoluted tubule
PCV packed cell volume
PII primary irritation index
ppm parts per million
RBC red blood cells
SAP serum alkaline phosphatase
s.c. subcutaneous(ly)
SG specific gravity
SGOT serum glutamate-oxalatetransaminase
SGPT serum glutamate-pyruvatetransaminase
SKF-525A 2-(diethylamino)ethyl diphenyl propyl acetate
t´ half-life
TAN tropical ataxia neuropathy
TGA total glycoalkaloids
TOS total organic solids
TOSO thermally oxidized soyabean oil
TOSOM thermally oxidized soyabean oil interacted with mono-
and diglycerides
v/v volume/volume
WBC white blood cell
WHO World Health Organization