ANNEX 2
ABBREVIATIONS USED IN THE MONOGRAPHS
AAF 2-acetylaminofluorene
ADI acceptable daily intake
A/G albumin/globulin ratio
AIIBP Association Internationale de L`Industrie des
Bouillons et Potages
Alk-P-ase alkaline phosphatase
ALAT alanine aminotransferase
AMP adenosine monophosphate
ANFT 2-amino-(5-nitro-furyl)thiazole
ASAT aspartate aminotransferase
ATP adenosine triphosphate
AUC area under curve
BBN N-butyl-N-(-hydroxy- butyl)nitrosamine
BHA butylated hydroxyanisole
BHT butylated hydroxytoluene
BSP bromosulfophthalein
BUN blood urea nitrogen
bw body weight
C control group
CFR Code of Federal Regulations (USA)
CGT cyclodextrin glycosyl transferase
CHO Chinese hamster ovary
CMC carboxymethylcellulose
Comm Community
cP centipoise (viscosity measure)
d day
D20 dose at which structural aberrations were detected in
20% of the metaphases observed
DBCP 1,2-dibromo-3-chloropropane
DEHP di-[2-ethylhexyl]phthalate
derm dermal
DiEHA ethylhexanedioic acid
Diff differential leucocytes
DMBA 7,12 dimethyl-1,2-benzanthracene
DMH 1,2-dimethylhydrazine
DNA deoxyribonucleic acid
Ds Dunaliella salina
dy day
EA 2-ethylhexanoic acid
EC50 effective concentration, median
EDA ethylene diamine
ED50 effective dose, median
EEC European Economic Community
EHA ethylhexanoic acid
EH 2-Ethylhexanol
EHEN N-ethyl-N-hydroxy ethylnitrosamine
EPA Environmental Protection Agency (U.S.)
Er erythrocytes
EROD hepatic ethoxy-resorufin-O-deethylase
ESR erythrocyte sedimentation rate
F female
F1 filial generation, first
F2 filial generation, second
FANFT N-[-(5-nitro-2-furyl)-thiazolyl]formamide
FAO Food and Agriculture Organization of the United
Nations
FBG fasting blood glucose
FEMA Flavor and Extract Manufacturers' Association of the
United States
FEP free erythrocyte protoporphyrin
GHB glycosylated haemoglobin
GI gastrointestinal
GIP gastric inhibitory polypeptide
GMP Disodium 5'-guanylate (guanylic acid, disodium salt)
G6Pase glucose-6-phosphatase
GRAS food chemicals generally recognized as safe
h hour
H high dose
Hb haemoglobin
HDL high-density lipoprotein
HDL-C high-density lipoprotein cholesterol
HeLa Helen Lane
HHS Department of Health and Human Services (USA)
HPF high polyunsaturated fat
HPLC high performance liquid chromatography
HSF high saturated fat
Hct haematocrit
IARC International Agency for Research on Cancer
IBT Industrial Bio-Test Labs., Inc.
ICG indocyanine green
ID50 inhibitory dose, 50%
ID iron deficiency
IDA iron deficiency anaemia
im intramuscular
IMP disodium 5'-inosinate
inh inhalation
IPCS International Programme on Chemical Safety
ip intraperitoneal
IRDC International Research and Development Corporation
iv intravenous
JECFA Joint FAO/WHO Expert Committee on Food Additives
KM konjac flour, konjac mannan
L low dose
LD50 lethal dose, median
LDH lactate dehydrogenase
LDL-C low-density lipoprotein cholesterol
LDLO lethal dose, lowest
Leu leucocytes
LF low fat
m male
MCHC mean corpuscular haemoglobin concentration
3-MCPD 3-chloro-1,2-propanediol (3-monochloropropane-1,2-
diol)
MCV mean cell volume
MEHP mono-[2-ethylhexyl]phthalate
MFO mixed function oxidase
mg milligram
min minute
MNNG N-methyl-N-nitrosoguanidine
MNU methyl-N-nitrosourea
MRI Midwest Research Institute
MSG monosodium glutamate
MTD maximum tolerated dose
mU 1/1000 International Unit insulin, 1 IU=0.04167 mg of
international standard preparation
NaFeEDTA sodium iron EDTA
NBR NCI-Black-Reiter (rats)
NEL no-effect-level
NOAEL no-observed-adverse-effect-level
NOEL no-observed-effect level
NQO nitroquinoline oxide
NTP National Toxicology Program (USA)
OCT ornithine carbamyl transferase
ODC ornithine decarboxylase
5-OH EHA 5-hydroxyethylhexanoic acid
PAS periodic acid Shiff
PBG 2-hour post-prandial blood glucose
pc percutaneous
PCV packed red cell volume
PG propyl gallate
PGA propylene glycol alginate
PN papillary or nodular hyperplasia
PNG Phillipines natural grade [carrageenan]
po by mouth
ppm parts per million
PSP phenosulfophthalein
RNA ribonucleic acid
RTP Research Triangle Park, NC (USA)
SAIB sucrose acetate isobutyrate
SAP serum alkaline phosphatase
% Sat % Saturation of Transferrin
s.c. subcutaneous(ly)
SCF soya-bean cotyledon fiber
SER smooth endoplasmic reticulum
SHADIB sucrose hexaacetate diisobutyrate
SLRL sex-linked recessive lethal
SOIB sucrose octaisobutyrate
tยด half-life
TBHQ tertiary butylhydroquinone
TC total cholesterol
TG triglyceride
TR frequency of cells with exchange type aberrations per
unit dose (mg/ml)
USEPA United States Environmental Protection Agency
v/v volume/volume
WBC white blood cell
WHO World Health Organization
See Also:
Toxicological Abbreviations