ANNEX 2

    ABBREVIATIONS USED IN THE MONOGRAPHS

    AAF            2-acetylaminofluorene
    ADI            acceptable daily intake
    ALAT           alaninc aminotransferase
    ALP            alkaline phosphatase
    ASAT           aspartate aminotransferase
    ATP            adenosine triphosphate
    AUC            area under the curve

    BHA            butylated hydroxy anisole
    BUN            blood urea nitrogen
    bw             body weight

    CHO            Chinese hamster ovary
    CMC            carboxymethyl cellulose
    CNS            central nervous system
    CV             conventional flora

    DMSO           dimethylsulfoxide
    DNA            deoxyribonucleic acid

    ECG            electrocardiogram
    ED50           effective dose, median
    ERG            electroretinogram

    F              female
    F1             filial generation, first
    F2             filial generation, second
    FAO            Food and Agriculture Organization of the United
                     Nations
    FDA            US Food and Drug Administration

    g              gram
    gamma-GT       gamma glutamyl transferase
    GC             gas chromatography
    GF             germ-free
    GI             gastrointestinal
    GLP            good laboratory practice
    GOT            glutamate oxalate transaminase
    GPT            glutmate pyruvate transaminase
    GSH            glutathione

    h              hour
    H & E          hematoxylin and eosin stain
    Hb             haemoglobin
    HDL            high density lipoprotein
    HPLC           high performance liquid chromatography

    i.m.           intramuscular
    i.p.           intraperitoneal
    i.v.           intravenous
    IARC           International Agency for Research on Cancer
    IPCS           International Programme on Chemical Safety

    JECFA          Joint FAO/WHO Expert Committee on Food Additives

    kg             kilogram

    l              litre
    LD50           lethal dose, median
    LDH            lactate dehydrogenase

    M              male
    MCH            mean corpuscular haemoglobin
    MCV            mean corpuscular volume
    MetHb          methaemoglobin
    mg             milligram
    ml             millilitre
    MS             mass spectrometry
    MTD            maximum tolerated dose

    NADPH          nicotinamide adenine dinucleotide phosphate
                     (reduced)
    NMR            nuclear magnetic resonance
    NOAEL          no-observed-adverse-effect level
    NOEL           no-observed-effect level

    OCT            ornithine carbamyl transferase

    PAS            para-aminosalicylic acid
    p.o.           per os (by mouth)
    PCV            packed cell volume
    PT             prothrombin time
    PTWI           provisional tolerable weekly intake

    RBC            red blood cell count
    RNA            ribonucleic acid

    s.c.           subcutaneous
    SCE            sister chromatid exchange
    SEM            scanning electron microscopy
    SGOT           serum glutamate-oxalate transaminase
    SGPT           serum glutamate-pyruvate transaminase

    TSH            thyroid-stimulating hormone

    UDS            unscheduled DNA synthesis

    v/v            volume per volume

    WBC            white blood cell
    WHO            World Health Organization
    

    See Also:
       Toxicological Abbreviations